Reversion inducing cysteine rich protein with Kazal motifs and cardiovascular diseases: The RECKlessness of adverse remodeling

The Reversion Inducing Cysteine Rich Protein With Kazal Motifs (RECK) is a glycosylphosphatidylinositol (GPI) anchored membrane-bound regulator of matrix metalloproteinases (MMPs). It is expressed throughout the body and plays a role in extracellular matrix (ECM) homeostasis and inflammation. In ini...

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Veröffentlicht in:	Cellular signalling 2021-07, Vol.83, p.109993-109993, Article 109993
Hauptverfasser:	Russell, Jacob J., Grisanti, Laurel A., Brown, Scott M., Bailey, Chastidy A., Bender, Shawn B., Chandrasekar, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse remodeling Cell Movement Down-Regulation EGFR Extracellular Matrix - genetics Extracellular Matrix - metabolism Fibrosis GPI-Linked Proteins - biosynthesis GPI-Linked Proteins - genetics Humans Inflammation Kazal Motifs Metallopeptidases RECK Signal Transduction Vascular Remodeling
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