Addition of mirror-image L-DNA elements to DNA amplification circuits to distinguish leakage from target signal

DNA amplification circuits that rely on thermodynamically-driven hybridization events triggered by a target nucleic acid are becoming increasingly utilized due to their relative simplicity. A drawback of these circuits is that non-specific amplification, or circuit leakage, must be estimated using a...

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Veröffentlicht in:	Biosensors & bioelectronics 2021-09, Vol.188, p.113354-113354, Article 113354
Hauptverfasser:	Zimmers, Zackary A., Adams, Nicholas M., Haselton, Frederick R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysics Biotechnology & Applied Microbiology Catalyzed hairpin assembly Chemistry Chemistry, Analytical DNA circuits Electrochemistry Fluorescence L-DNA Leakage Life Sciences & Biomedicine Nanoscience & Nanotechnology Physical Sciences Science & Technology Science & Technology - Other Topics
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