Spectroscopic and In Silico Studies on the Interaction of Substituted Pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one Derivatives with c-Myc G4-DNA

Herein we describe a combined experimental and in silico study of the interaction of a series of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives (PBTs) with parallel G-quadruplex (GQ) DNA aimed at correlating their previously reported anticancer activities and the stabilizing effects observe...

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Veröffentlicht in:International journal of molecular sciences 2021-06, Vol.22 (11), p.6028, Article 6028
Hauptverfasser: Mulliri, Simone, Laaksonen, Aatto, Spanu, Pietro, Farris, Riccardo, Farci, Matteo, Mingoia, Francesco, Roviello, Giovanni N., Mocci, Francesca
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Sprache:eng
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