Cyclovirobuxine D Induced-Mitophagy through the p65/BNIP3/LC3 Axis Potentiates Its Apoptosis-Inducing Effects in Lung Cancer Cells

Mitophagy plays a pro-survival or pro-death role that is cellular-context- and stress-condition-dependent. In this study, we revealed that cyclovirobuxine D (CVB-D), a natural compound derived from Buxus microphylla, was able to provoke mitophagy in lung cancer cells. CVB-D-induced mitophagy potenti...

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Veröffentlicht in:International journal of molecular sciences 2021-05, Vol.22 (11), p.5820
Hauptverfasser: Zeng, Cheng, Zou, Tingting, Qu, Junyan, Chen, Xu, Zhang, Suping, Lin, Zhenghong
Format: Artikel
Sprache:eng
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