WNT4 Balances Development vs Disease in Gynecologic Tissues and Women’s Health

The WNT family of proteins is crucial in numerous developmental pathways and tissue homeostasis. WNT4, in particular, is uniquely implicated in the development of the female phenotype in the fetus, and in the maintenance of müllerian and reproductive tissues. WNT4 dysfunction or dysregulation can dr...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2021-07, Vol.162 (7)
Hauptverfasser:	Pitzer, Lauren M, Moroney, Marisa R, Nokoff, Natalie J, Sikora, Matthew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast cancer Breast Neoplasms - genetics Cancer Endocrinology Endometriosis Estrogen receptors Estrogens Female Fetuses Fibroids Gene expression Genital Diseases, Female - genetics Genitalia, Female Homeostasis Humans Infertility Mammary Glands, Human - physiology Mice Mini-Reviews Mutation Nucleotides Ovarian cancer Phenotypes Polymorphism, Single Nucleotide - genetics Pregnancy Sex Sex determination Sex Differentiation - physiology Sex reversal Sexual Development - physiology Signal transduction Single-nucleotide polymorphism Tissues Uterus - physiology Wnt protein Wnt4 Protein - genetics Wnt4 Protein - physiology Women Women's Health Womens health
Online-Zugang:	Volltext
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