A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive reperto...

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Veröffentlicht in:	Cell 2021-06, Vol.184 (12), p.3222-3241.e26
Hauptverfasser:	Yao, Zizhen, van Velthoven, Cindy T.J., Nguyen, Thuc Nghi, Goldy, Jeff, Sedeno-Cortes, Adriana E., Baftizadeh, Fahimeh, Bertagnolli, Darren, Casper, Tamara, Chiang, Megan, Crichton, Kirsten, Ding, Song-Lin, Fong, Olivia, Garren, Emma, Glandon, Alexandra, Gouwens, Nathan W., Gray, James, Graybuck, Lucas T., Hawrylycz, Michael J., Hirschstein, Daniel, Kroll, Matthew, Lathia, Kanan, Lee, Changkyu, Levi, Boaz, McMillen, Delissa, Mok, Stephanie, Pham, Thanh, Ren, Qingzhong, Rimorin, Christine, Shapovalova, Nadiya, Sulc, Josef, Sunkin, Susan M., Tieu, Michael, Torkelson, Amy, Tung, Herman, Ward, Katelyn, Dee, Nick, Smith, Kimberly A., Tasic, Bosiljka, Zeng, Hongkui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cell type cortex excitatory neuron GABAergic GABAergic Neurons - cytology GABAergic Neurons - metabolism glutamatergic Glutamic Acid - metabolism hippocampus Hippocampus - cytology interneuron Mice Mice, Inbred C57BL Mice, Transgenic Neocortex - cytology single-cell RNA sequencing single-cell transcriptomics Transcriptome - genetics
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