Microbiota regulate innate immune signaling and protective immunity against cancer

Microbiota play critical roles in regulating colitis and colorectal cancer (CRC). However, it is unclear how the microbiota generate protective immunity against these disease states. Here, we find that loss of the innate and adaptive immune signaling molecule, TAK1, in myeloid cells (Tak1ΔM/ΔM) yiel...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell host & microbe 2021-06, Vol.29 (6), p.959-974.e7
Hauptverfasser:	Xing, Changsheng, Wang, Mingjun, Ajibade, Adebusola A., Tan, Peng, Fu, Chuntang, Chen, Lang, Zhu, Motao, Hao, Zhao-Zhe, Chu, Junjun, Yu, Xiao, Yin, Bingnan, Zhu, Jiahui, Shen, Wan-Jou, Duan, Tianhao, Wang, Helen Y., Wang, Rong-Fu
Format:	Artikel
Sprache:	eng
Schlagworte:	acute colitis Bacteroides sp. D20 colon cancer innate immunity microbiota Odoribacter splanchnicus TAK1 signaling Th17 cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!