Precision ejection of microfluidic droplets into air with a superhydrophobic outlet
Dispensing micron-scale droplets from a suspended nozzle is important for applications in bioprinting, analytical chemistry, and pharmaceutical formulation. Here, we describe a general approach to eject droplets from microfluidic devices using superhydrophobic patterning; this facilitates release of...
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| Veröffentlicht in: | Lab on a chip 2021-04, Vol.21 (8), p.1484-1491 |
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| container_title | Lab on a chip |
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| creator | Zhang, Pengfei Chang, Kai-Chun Abate, Adam R |
| description | Dispensing micron-scale droplets from a suspended nozzle is important for applications in bioprinting, analytical chemistry, and pharmaceutical formulation. Here, we describe a general approach to eject droplets from microfluidic devices using superhydrophobic patterning; this facilitates release of wetted fluids, allowing droplets to break contact with channel surfaces and travel along regular paths to achieve a printing accuracy of ∼3 μm. We demonstrate the utility of the approach by using it to print droplets of varied composition from a microfluidic mixing device. Our approach is compatible with common fabrication techniques making it applicable to devices configured for diverse applications.
We describe a general approach to controllably and precisely eject droplets of tunable composition from microfluidic devices using superhydrophobic patterning. |
| doi_str_mv | 10.1039/d0lc01327g |
| format | Article |
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We describe a general approach to controllably and precisely eject droplets of tunable composition from microfluidic devices using superhydrophobic patterning.</description><identifier>ISSN: 1473-0197</identifier><identifier>EISSN: 1473-0189</identifier><identifier>DOI: 10.1039/d0lc01327g</identifier><identifier>PMID: 33656500</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Analytical chemistry ; Bioengineering ; Droplets ; Hydrophobic and Hydrophilic Interactions ; Hydrophobic surfaces ; Hydrophobicity ; Lab-On-A-Chip Devices ; Microfluidic Analytical Techniques ; Microfluidic devices ; Microfluidics ; Nozzles ; Three dimensional printing</subject><ispartof>Lab on a chip, 2021-04, Vol.21 (8), p.1484-1491</ispartof><rights>Copyright Royal Society of Chemistry 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-32fae65d1a4a388cbcdba5e2a07887d2ab4b43e03137461230a774164ccfe8713</citedby><cites>FETCH-LOGICAL-c491t-32fae65d1a4a388cbcdba5e2a07887d2ab4b43e03137461230a774164ccfe8713</cites><orcidid>0000-0002-9458-5067</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27915,27916</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33656500$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Pengfei</creatorcontrib><creatorcontrib>Chang, Kai-Chun</creatorcontrib><creatorcontrib>Abate, Adam R</creatorcontrib><title>Precision ejection of microfluidic droplets into air with a superhydrophobic outlet</title><title>Lab on a chip</title><addtitle>Lab Chip</addtitle><description>Dispensing micron-scale droplets from a suspended nozzle is important for applications in bioprinting, analytical chemistry, and pharmaceutical formulation. Here, we describe a general approach to eject droplets from microfluidic devices using superhydrophobic patterning; this facilitates release of wetted fluids, allowing droplets to break contact with channel surfaces and travel along regular paths to achieve a printing accuracy of ∼3 μm. We demonstrate the utility of the approach by using it to print droplets of varied composition from a microfluidic mixing device. Our approach is compatible with common fabrication techniques making it applicable to devices configured for diverse applications.
We describe a general approach to controllably and precisely eject droplets of tunable composition from microfluidic devices using superhydrophobic patterning.</description><subject>Analytical chemistry</subject><subject>Bioengineering</subject><subject>Droplets</subject><subject>Hydrophobic and Hydrophilic Interactions</subject><subject>Hydrophobic surfaces</subject><subject>Hydrophobicity</subject><subject>Lab-On-A-Chip Devices</subject><subject>Microfluidic Analytical Techniques</subject><subject>Microfluidic devices</subject><subject>Microfluidics</subject><subject>Nozzles</subject><subject>Three dimensional printing</subject><issn>1473-0197</issn><issn>1473-0189</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0c9LwzAUB_AgitPpxbtS8CJCNb_atBdBpk5hoKCeQ5qma0bbzKRV9t-bull_nPLgfXi8vC8ARwheIEjSyxxWEiKC2XwL7CHKSAhRkm4PdcpGYN-5BYQoonGyC0aExFEcQbgHnp-sktpp0wRqoWTbF6YIai2tKapO51oGuTXLSrUu0E1rAqFt8KHbMhCB65bKlqu-X5rMS9O1Hh6AnUJUTh1u3jF4vbt9mdyHs8fpw-R6FkqaojYkuBAqjnIkqCBJIjOZZyJSWECWJCzHIqMZJQoSRBiNESZQMEZRTKUsVMIQGYOr9dxll9Uql6ppraj40upa2BU3QvO_nUaXfG7eeeLPE6fUDzjbDLDmrVOu5bV2UlWVaJTpHMc0jXGE_KE8Pf1HF6azjf8e7wXC2DOvztfKX885q4phGQR5nxW_gbPJV1ZTj09-rz_Q73A8OF4D6-TQ_QmbfAIlrZoS</recordid><startdate>20210420</startdate><enddate>20210420</enddate><creator>Zhang, Pengfei</creator><creator>Chang, Kai-Chun</creator><creator>Abate, Adam R</creator><general>Royal Society of Chemistry</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>L7M</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9458-5067</orcidid></search><sort><creationdate>20210420</creationdate><title>Precision ejection of microfluidic droplets into air with a superhydrophobic outlet</title><author>Zhang, Pengfei ; Chang, Kai-Chun ; Abate, Adam R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-32fae65d1a4a388cbcdba5e2a07887d2ab4b43e03137461230a774164ccfe8713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Analytical chemistry</topic><topic>Bioengineering</topic><topic>Droplets</topic><topic>Hydrophobic and Hydrophilic Interactions</topic><topic>Hydrophobic surfaces</topic><topic>Hydrophobicity</topic><topic>Lab-On-A-Chip Devices</topic><topic>Microfluidic Analytical Techniques</topic><topic>Microfluidic devices</topic><topic>Microfluidics</topic><topic>Nozzles</topic><topic>Three dimensional printing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Pengfei</creatorcontrib><creatorcontrib>Chang, Kai-Chun</creatorcontrib><creatorcontrib>Abate, Adam R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Lab on a chip</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Pengfei</au><au>Chang, Kai-Chun</au><au>Abate, Adam R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Precision ejection of microfluidic droplets into air with a superhydrophobic outlet</atitle><jtitle>Lab on a chip</jtitle><addtitle>Lab Chip</addtitle><date>2021-04-20</date><risdate>2021</risdate><volume>21</volume><issue>8</issue><spage>1484</spage><epage>1491</epage><pages>1484-1491</pages><issn>1473-0197</issn><eissn>1473-0189</eissn><abstract>Dispensing micron-scale droplets from a suspended nozzle is important for applications in bioprinting, analytical chemistry, and pharmaceutical formulation. Here, we describe a general approach to eject droplets from microfluidic devices using superhydrophobic patterning; this facilitates release of wetted fluids, allowing droplets to break contact with channel surfaces and travel along regular paths to achieve a printing accuracy of ∼3 μm. We demonstrate the utility of the approach by using it to print droplets of varied composition from a microfluidic mixing device. Our approach is compatible with common fabrication techniques making it applicable to devices configured for diverse applications.
We describe a general approach to controllably and precisely eject droplets of tunable composition from microfluidic devices using superhydrophobic patterning.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>33656500</pmid><doi>10.1039/d0lc01327g</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-9458-5067</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1473-0197 |
| ispartof | Lab on a chip, 2021-04, Vol.21 (8), p.1484-1491 |
| issn | 1473-0197 1473-0189 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8189694 |
| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Analytical chemistry Bioengineering Droplets Hydrophobic and Hydrophilic Interactions Hydrophobic surfaces Hydrophobicity Lab-On-A-Chip Devices Microfluidic Analytical Techniques Microfluidic devices Microfluidics Nozzles Three dimensional printing |
| title | Precision ejection of microfluidic droplets into air with a superhydrophobic outlet |
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