Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy
A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled m...
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| Veröffentlicht in: | Internal Medicine 2021/05/15, Vol.60(10), pp.1555-1560 |
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| creator | Yokota, Kenichi Kurihara, Isao Matsusaka, Yohji Emoto, Katsura Hishida, Tomoyuki Oshida, Takuma Kobayashi, Sakiko Murai-Takeda, Ayano Miyashita, Kazutoshi Matsuda, Kohei Nakagomi, Takahiro Matsuda, Kosuke Itoh, Hiroshi |
| description | A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (99mTc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor. |
| doi_str_mv | 10.2169/internalmedicine.6381-20 |
| format | Article |
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He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (99mTc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.6381-20</identifier><identifier>PMID: 33281167</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>111In-pentetreotide scintigraphy ; Adenoma ; Adenoma - diagnostic imaging ; Adenoma - surgery ; Aged ; Appetite loss ; Case Report ; Computed tomography ; ectopic parathyroid adenoma ; Humans ; Hyperparathyroidism ; Internal medicine ; Male ; Mediastinum ; Nausea ; Parathyroid ; Parathyroid Glands ; Parathyroid hormone ; Parathyroid Neoplasms - diagnostic imaging ; Parathyroid Neoplasms - surgery ; primary hyperparathyroidism ; Radionuclide Imaging ; Radiopharmaceuticals ; Receptors, Somatostatin ; Scintigraphy ; Somatostatin ; somatostatin receptor scintigraphy ; Surgery ; Technetium ; Technetium Tc 99m Sestamibi ; Tomography ; Tomography, Emission-Computed, Single-Photon ; Tumors</subject><ispartof>Internal Medicine, 2021/05/15, Vol.60(10), pp.1555-1560</ispartof><rights>2021 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2021</rights><rights>Copyright © 2021 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c667t-fc8895ce9c5946aab7a38db8c4d31bd08ac2a2bf0554ba6eca02bf2dd27ebd393</citedby><cites>FETCH-LOGICAL-c667t-fc8895ce9c5946aab7a38db8c4d31bd08ac2a2bf0554ba6eca02bf2dd27ebd393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188027/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8188027/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,1883,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33281167$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yokota, Kenichi</creatorcontrib><creatorcontrib>Kurihara, Isao</creatorcontrib><creatorcontrib>Matsusaka, Yohji</creatorcontrib><creatorcontrib>Emoto, Katsura</creatorcontrib><creatorcontrib>Hishida, Tomoyuki</creatorcontrib><creatorcontrib>Oshida, Takuma</creatorcontrib><creatorcontrib>Kobayashi, Sakiko</creatorcontrib><creatorcontrib>Murai-Takeda, Ayano</creatorcontrib><creatorcontrib>Miyashita, Kazutoshi</creatorcontrib><creatorcontrib>Matsuda, Kohei</creatorcontrib><creatorcontrib>Nakagomi, Takahiro</creatorcontrib><creatorcontrib>Matsuda, Kosuke</creatorcontrib><creatorcontrib>Itoh, Hiroshi</creatorcontrib><title>Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (99mTc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor.</description><subject>111In-pentetreotide scintigraphy</subject><subject>Adenoma</subject><subject>Adenoma - diagnostic imaging</subject><subject>Adenoma - surgery</subject><subject>Aged</subject><subject>Appetite loss</subject><subject>Case Report</subject><subject>Computed tomography</subject><subject>ectopic parathyroid adenoma</subject><subject>Humans</subject><subject>Hyperparathyroidism</subject><subject>Internal medicine</subject><subject>Male</subject><subject>Mediastinum</subject><subject>Nausea</subject><subject>Parathyroid</subject><subject>Parathyroid Glands</subject><subject>Parathyroid hormone</subject><subject>Parathyroid Neoplasms - diagnostic imaging</subject><subject>Parathyroid Neoplasms - surgery</subject><subject>primary hyperparathyroidism</subject><subject>Radionuclide Imaging</subject><subject>Radiopharmaceuticals</subject><subject>Receptors, Somatostatin</subject><subject>Scintigraphy</subject><subject>Somatostatin</subject><subject>somatostatin receptor scintigraphy</subject><subject>Surgery</subject><subject>Technetium</subject><subject>Technetium Tc 99m Sestamibi</subject><subject>Tomography</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Tumors</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkduO0zAQhi0EYsvCK6BI3HCTxYfEsW-QVl1O0qJFLHBrTexp6yqNi-0i5e1x1FLBipvx6Zt_xvMTUjF6xZnUb_yYMY4w7NB560e8kkKxmtNHZMFEo-uOi_YxWVDNVM1LuCDPUtpSKlSn-VNyIQRXjMluQX58LhKQsi9q1XIqG1t9gQh5M8XgXXXtcAw7qG48rMeQ0FX9VN2XmxxShpJWfUWL-xxidV86yX4dYb-ZnpMnKxgSvjitl-T7-3fflh_r27sPn5bXt7WVssv1yiqlW4vatrqRAH0HQrle2cYJ1juqwHLg_Yq2bdODRAu0nLhzvMPeCS0uyduj7v7Ql2FYHHOEweyj30GcTABv_n0Z_caswy-jmFKUd0Xg9Ukghp8HTNnsfLI4DDBiOCTDG9mpppNiRl89QLfhMLtQqFa0mmvVskKpI2VjSCni6twMo2Y2zzw0z8zmGU5L6su_P3NO_ONWAe6OwLbMfo1nAGKxbcD_KNO5aomnEmfSbiAaHMVveTq7ow</recordid><startdate>20210515</startdate><enddate>20210515</enddate><creator>Yokota, Kenichi</creator><creator>Kurihara, Isao</creator><creator>Matsusaka, Yohji</creator><creator>Emoto, Katsura</creator><creator>Hishida, Tomoyuki</creator><creator>Oshida, Takuma</creator><creator>Kobayashi, Sakiko</creator><creator>Murai-Takeda, Ayano</creator><creator>Miyashita, Kazutoshi</creator><creator>Matsuda, Kohei</creator><creator>Nakagomi, Takahiro</creator><creator>Matsuda, Kosuke</creator><creator>Itoh, Hiroshi</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210515</creationdate><title>Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy</title><author>Yokota, Kenichi ; Kurihara, Isao ; Matsusaka, Yohji ; Emoto, Katsura ; Hishida, Tomoyuki ; Oshida, Takuma ; Kobayashi, Sakiko ; Murai-Takeda, Ayano ; Miyashita, Kazutoshi ; Matsuda, Kohei ; Nakagomi, Takahiro ; Matsuda, Kosuke ; Itoh, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c667t-fc8895ce9c5946aab7a38db8c4d31bd08ac2a2bf0554ba6eca02bf2dd27ebd393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>111In-pentetreotide scintigraphy</topic><topic>Adenoma</topic><topic>Adenoma - diagnostic imaging</topic><topic>Adenoma - surgery</topic><topic>Aged</topic><topic>Appetite loss</topic><topic>Case Report</topic><topic>Computed tomography</topic><topic>ectopic parathyroid adenoma</topic><topic>Humans</topic><topic>Hyperparathyroidism</topic><topic>Internal medicine</topic><topic>Male</topic><topic>Mediastinum</topic><topic>Nausea</topic><topic>Parathyroid</topic><topic>Parathyroid Glands</topic><topic>Parathyroid hormone</topic><topic>Parathyroid Neoplasms - diagnostic imaging</topic><topic>Parathyroid Neoplasms - surgery</topic><topic>primary hyperparathyroidism</topic><topic>Radionuclide Imaging</topic><topic>Radiopharmaceuticals</topic><topic>Receptors, Somatostatin</topic><topic>Scintigraphy</topic><topic>Somatostatin</topic><topic>somatostatin receptor scintigraphy</topic><topic>Surgery</topic><topic>Technetium</topic><topic>Technetium Tc 99m Sestamibi</topic><topic>Tomography</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yokota, Kenichi</creatorcontrib><creatorcontrib>Kurihara, Isao</creatorcontrib><creatorcontrib>Matsusaka, Yohji</creatorcontrib><creatorcontrib>Emoto, Katsura</creatorcontrib><creatorcontrib>Hishida, Tomoyuki</creatorcontrib><creatorcontrib>Oshida, Takuma</creatorcontrib><creatorcontrib>Kobayashi, Sakiko</creatorcontrib><creatorcontrib>Murai-Takeda, Ayano</creatorcontrib><creatorcontrib>Miyashita, Kazutoshi</creatorcontrib><creatorcontrib>Matsuda, Kohei</creatorcontrib><creatorcontrib>Nakagomi, Takahiro</creatorcontrib><creatorcontrib>Matsuda, Kosuke</creatorcontrib><creatorcontrib>Itoh, Hiroshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yokota, Kenichi</au><au>Kurihara, Isao</au><au>Matsusaka, Yohji</au><au>Emoto, Katsura</au><au>Hishida, Tomoyuki</au><au>Oshida, Takuma</au><au>Kobayashi, Sakiko</au><au>Murai-Takeda, Ayano</au><au>Miyashita, Kazutoshi</au><au>Matsuda, Kohei</au><au>Nakagomi, Takahiro</au><au>Matsuda, Kosuke</au><au>Itoh, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2021-05-15</date><risdate>2021</risdate><volume>60</volume><issue>10</issue><spage>1555</spage><epage>1560</epage><pages>1555-1560</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (99mTc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>33281167</pmid><doi>10.2169/internalmedicine.6381-20</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 111In-pentetreotide scintigraphy Adenoma Adenoma - diagnostic imaging Adenoma - surgery Aged Appetite loss Case Report Computed tomography ectopic parathyroid adenoma Humans Hyperparathyroidism Internal medicine Male Mediastinum Nausea Parathyroid Parathyroid Glands Parathyroid hormone Parathyroid Neoplasms - diagnostic imaging Parathyroid Neoplasms - surgery primary hyperparathyroidism Radionuclide Imaging Radiopharmaceuticals Receptors, Somatostatin Scintigraphy Somatostatin somatostatin receptor scintigraphy Surgery Technetium Technetium Tc 99m Sestamibi Tomography Tomography, Emission-Computed, Single-Photon Tumors |
| title | Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy |
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