Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study
Abstract Objectives The aim of this study was to evaluate the effects of 2% chlorhexidine gluconate (CHG) and 2% sodium fluoride (NaF) as endodontic irrigants on microhardness of root dentin. Materials and Methods In this in vitro study, access cavity and root canal preparations were done on 24 fr...
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| Veröffentlicht in: | European journal of dentistry 2021-05, Vol.15 (2), p.253-258 |
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| creator | Kulkarni, Sangeeta Mustafa, Mohammed Ghatole, Kiran AlQahtani, Ali Robaian I. Asiri, Faris Yahya Alghomlas, Ziyad Ibrahim Alothman, Tameem Abdullah Alhajri, Fawaz Fahad |
| description | Abstract
Objectives
The aim of this study was to evaluate the effects of 2% chlorhexidine gluconate (CHG) and 2% sodium fluoride (NaF) as endodontic irrigants on microhardness of root dentin.
Materials and Methods
In this
in vitro
study, access cavity and root canal preparations were done on 24 freshly extracted anterior teeth. After sectioning into 24 dentin discs using hard tissue microtome in 2 mm thickness, all samples were immersed in solutions of 17% ethylenediamine tetra-acetic acid (EDTA) (2 minutes) followed by 2.5% of sodium hypochlorite (NaOCl) (10 minutes). Then samples were randomly divided into three groups based on the irrigant used: Group I: saline (control group); Group II: 2% NaF; Group III: 2% CHG for two minutes each. Dentin microhardness was measured before (pretreatment), during (after treatment with 17% EDTA and 2.5% NaOCl), and after the experimental period (after treatment with saline, 2% NaF, and 2% CHG) using a Vickers indenter. Statistical evaluation of the data was done using one-way analysis of variance (ANOVA) and the Student’s
t
-test, and the values are tabulated.
Results
Specimens rinsed in 2% CHG showed a significant increase in Vickers hardness number (VHN) values (
p
< 0.05), as compared with EDTA and NaOCl groups, whereas saline and 2% NaF groups showed no significant difference.
Conclusions
NaF did not show any significant effect on microhardness of the root dentin. CHG as an irrigant was seen to have a strengthening effect on dentin microhardness in comparison to NaOCl and EDTA, which has decreased the strength of root dentin. |
| doi_str_mv | 10.1055/s-0040-1717053 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8184278</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2449961713</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3203-33eddb7c9d8ecf1686550ea34badf74e29886405616dfdd186230ec051179cc43</originalsourceid><addsrcrecordid>eNp1kU9PHCEYh4mxUWu9eubSxMtYGP7MTA9NzHbVTWyaaNsrYeGdHcwMWBhM_Qj91rLZjUkPPUFenvd5gR9C55RcUiLEp1QRwklFG9oQwQ7QCWVEVA2X_PBtL-Qxep_SIyGSya47QseMEVYzxk_Q3-WzHrOeXfA49Lj-iBfDGOIAf5x1HrD2dlt8CNblCV-POURnSznhpbfBBj87g1cxuk1x-E0Bx7yVJVyE9yHM-CsUppi-ORPDoKP1kNJnfOXxyuNfbo4BP8zZvnxA73o9Jjjbr6fo5_Xyx-K2uvt-s1pc3VWG1YRVjIG168Z0tgXTU9lKIQhoxtfa9g2HumtbyYmQVNreWtrKmhEwRFDadMZwdoq-7LxPeT2BNeV6UY_qKbpJxxcVtFP_nng3qE14Vi1ted20RXCxF8TwO0Oa1eSSgXHUHkJOqua862RJhBX0coeWp6cUoX8bQ4na5qeS2uan9vmVhmrXMA8OJlCPIUdffuN__CscOJuB</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2449961713</pqid></control><display><type>article</type><title>Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Thieme Connect Journals Open Access</source><creator>Kulkarni, Sangeeta ; Mustafa, Mohammed ; Ghatole, Kiran ; AlQahtani, Ali Robaian ; I. Asiri, Faris Yahya ; Alghomlas, Ziyad Ibrahim ; Alothman, Tameem Abdullah ; Alhajri, Fawaz Fahad</creator><creatorcontrib>Kulkarni, Sangeeta ; Mustafa, Mohammed ; Ghatole, Kiran ; AlQahtani, Ali Robaian ; I. Asiri, Faris Yahya ; Alghomlas, Ziyad Ibrahim ; Alothman, Tameem Abdullah ; Alhajri, Fawaz Fahad</creatorcontrib><description>Abstract
Objectives
The aim of this study was to evaluate the effects of 2% chlorhexidine gluconate (CHG) and 2% sodium fluoride (NaF) as endodontic irrigants on microhardness of root dentin.
Materials and Methods
In this
in vitro
study, access cavity and root canal preparations were done on 24 freshly extracted anterior teeth. After sectioning into 24 dentin discs using hard tissue microtome in 2 mm thickness, all samples were immersed in solutions of 17% ethylenediamine tetra-acetic acid (EDTA) (2 minutes) followed by 2.5% of sodium hypochlorite (NaOCl) (10 minutes). Then samples were randomly divided into three groups based on the irrigant used: Group I: saline (control group); Group II: 2% NaF; Group III: 2% CHG for two minutes each. Dentin microhardness was measured before (pretreatment), during (after treatment with 17% EDTA and 2.5% NaOCl), and after the experimental period (after treatment with saline, 2% NaF, and 2% CHG) using a Vickers indenter. Statistical evaluation of the data was done using one-way analysis of variance (ANOVA) and the Student’s
t
-test, and the values are tabulated.
Results
Specimens rinsed in 2% CHG showed a significant increase in Vickers hardness number (VHN) values (
p
< 0.05), as compared with EDTA and NaOCl groups, whereas saline and 2% NaF groups showed no significant difference.
Conclusions
NaF did not show any significant effect on microhardness of the root dentin. CHG as an irrigant was seen to have a strengthening effect on dentin microhardness in comparison to NaOCl and EDTA, which has decreased the strength of root dentin.</description><identifier>ISSN: 1305-7456</identifier><identifier>EISSN: 1305-7464</identifier><identifier>DOI: 10.1055/s-0040-1717053</identifier><identifier>PMID: 33032334</identifier><language>eng</language><publisher>A-12, Second Floor, Sector -2, NOIDA -201301, India: Thieme Medical and Scientific Publishers Private Ltd</publisher><subject>Original ; Original Article</subject><ispartof>European journal of dentistry, 2021-05, Vol.15 (2), p.253-258</ispartof><rights>European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)</rights><rights>European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) 2020 European Journal of Dentistry</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3203-33eddb7c9d8ecf1686550ea34badf74e29886405616dfdd186230ec051179cc43</citedby><cites>FETCH-LOGICAL-c3203-33eddb7c9d8ecf1686550ea34badf74e29886405616dfdd186230ec051179cc43</cites><orcidid>0000-0002-7957-3463</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184278/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184278/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,20872,27903,27904,53769,53771,54565,54593</link.rule.ids></links><search><creatorcontrib>Kulkarni, Sangeeta</creatorcontrib><creatorcontrib>Mustafa, Mohammed</creatorcontrib><creatorcontrib>Ghatole, Kiran</creatorcontrib><creatorcontrib>AlQahtani, Ali Robaian</creatorcontrib><creatorcontrib>I. Asiri, Faris Yahya</creatorcontrib><creatorcontrib>Alghomlas, Ziyad Ibrahim</creatorcontrib><creatorcontrib>Alothman, Tameem Abdullah</creatorcontrib><creatorcontrib>Alhajri, Fawaz Fahad</creatorcontrib><title>Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study</title><title>European journal of dentistry</title><addtitle>Eur J Dent</addtitle><description>Abstract
Objectives
The aim of this study was to evaluate the effects of 2% chlorhexidine gluconate (CHG) and 2% sodium fluoride (NaF) as endodontic irrigants on microhardness of root dentin.
Materials and Methods
In this
in vitro
study, access cavity and root canal preparations were done on 24 freshly extracted anterior teeth. After sectioning into 24 dentin discs using hard tissue microtome in 2 mm thickness, all samples were immersed in solutions of 17% ethylenediamine tetra-acetic acid (EDTA) (2 minutes) followed by 2.5% of sodium hypochlorite (NaOCl) (10 minutes). Then samples were randomly divided into three groups based on the irrigant used: Group I: saline (control group); Group II: 2% NaF; Group III: 2% CHG for two minutes each. Dentin microhardness was measured before (pretreatment), during (after treatment with 17% EDTA and 2.5% NaOCl), and after the experimental period (after treatment with saline, 2% NaF, and 2% CHG) using a Vickers indenter. Statistical evaluation of the data was done using one-way analysis of variance (ANOVA) and the Student’s
t
-test, and the values are tabulated.
Results
Specimens rinsed in 2% CHG showed a significant increase in Vickers hardness number (VHN) values (
p
< 0.05), as compared with EDTA and NaOCl groups, whereas saline and 2% NaF groups showed no significant difference.
Conclusions
NaF did not show any significant effect on microhardness of the root dentin. CHG as an irrigant was seen to have a strengthening effect on dentin microhardness in comparison to NaOCl and EDTA, which has decreased the strength of root dentin.</description><subject>Original</subject><subject>Original Article</subject><issn>1305-7456</issn><issn>1305-7464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>0U6</sourceid><recordid>eNp1kU9PHCEYh4mxUWu9eubSxMtYGP7MTA9NzHbVTWyaaNsrYeGdHcwMWBhM_Qj91rLZjUkPPUFenvd5gR9C55RcUiLEp1QRwklFG9oQwQ7QCWVEVA2X_PBtL-Qxep_SIyGSya47QseMEVYzxk_Q3-WzHrOeXfA49Lj-iBfDGOIAf5x1HrD2dlt8CNblCV-POURnSznhpbfBBj87g1cxuk1x-E0Bx7yVJVyE9yHM-CsUppi-ORPDoKP1kNJnfOXxyuNfbo4BP8zZvnxA73o9Jjjbr6fo5_Xyx-K2uvt-s1pc3VWG1YRVjIG168Z0tgXTU9lKIQhoxtfa9g2HumtbyYmQVNreWtrKmhEwRFDadMZwdoq-7LxPeT2BNeV6UY_qKbpJxxcVtFP_nng3qE14Vi1ted20RXCxF8TwO0Oa1eSSgXHUHkJOqua862RJhBX0coeWp6cUoX8bQ4na5qeS2uan9vmVhmrXMA8OJlCPIUdffuN__CscOJuB</recordid><startdate>20210501</startdate><enddate>20210501</enddate><creator>Kulkarni, Sangeeta</creator><creator>Mustafa, Mohammed</creator><creator>Ghatole, Kiran</creator><creator>AlQahtani, Ali Robaian</creator><creator>I. Asiri, Faris Yahya</creator><creator>Alghomlas, Ziyad Ibrahim</creator><creator>Alothman, Tameem Abdullah</creator><creator>Alhajri, Fawaz Fahad</creator><general>Thieme Medical and Scientific Publishers Private Ltd</general><scope>0U6</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7957-3463</orcidid></search><sort><creationdate>20210501</creationdate><title>Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study</title><author>Kulkarni, Sangeeta ; Mustafa, Mohammed ; Ghatole, Kiran ; AlQahtani, Ali Robaian ; I. Asiri, Faris Yahya ; Alghomlas, Ziyad Ibrahim ; Alothman, Tameem Abdullah ; Alhajri, Fawaz Fahad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3203-33eddb7c9d8ecf1686550ea34badf74e29886405616dfdd186230ec051179cc43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Original</topic><topic>Original Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kulkarni, Sangeeta</creatorcontrib><creatorcontrib>Mustafa, Mohammed</creatorcontrib><creatorcontrib>Ghatole, Kiran</creatorcontrib><creatorcontrib>AlQahtani, Ali Robaian</creatorcontrib><creatorcontrib>I. Asiri, Faris Yahya</creatorcontrib><creatorcontrib>Alghomlas, Ziyad Ibrahim</creatorcontrib><creatorcontrib>Alothman, Tameem Abdullah</creatorcontrib><creatorcontrib>Alhajri, Fawaz Fahad</creatorcontrib><collection>Thieme Connect Journals Open Access</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European journal of dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kulkarni, Sangeeta</au><au>Mustafa, Mohammed</au><au>Ghatole, Kiran</au><au>AlQahtani, Ali Robaian</au><au>I. Asiri, Faris Yahya</au><au>Alghomlas, Ziyad Ibrahim</au><au>Alothman, Tameem Abdullah</au><au>Alhajri, Fawaz Fahad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study</atitle><jtitle>European journal of dentistry</jtitle><addtitle>Eur J Dent</addtitle><date>2021-05-01</date><risdate>2021</risdate><volume>15</volume><issue>2</issue><spage>253</spage><epage>258</epage><pages>253-258</pages><issn>1305-7456</issn><eissn>1305-7464</eissn><abstract>Abstract
Objectives
The aim of this study was to evaluate the effects of 2% chlorhexidine gluconate (CHG) and 2% sodium fluoride (NaF) as endodontic irrigants on microhardness of root dentin.
Materials and Methods
In this
in vitro
study, access cavity and root canal preparations were done on 24 freshly extracted anterior teeth. After sectioning into 24 dentin discs using hard tissue microtome in 2 mm thickness, all samples were immersed in solutions of 17% ethylenediamine tetra-acetic acid (EDTA) (2 minutes) followed by 2.5% of sodium hypochlorite (NaOCl) (10 minutes). Then samples were randomly divided into three groups based on the irrigant used: Group I: saline (control group); Group II: 2% NaF; Group III: 2% CHG for two minutes each. Dentin microhardness was measured before (pretreatment), during (after treatment with 17% EDTA and 2.5% NaOCl), and after the experimental period (after treatment with saline, 2% NaF, and 2% CHG) using a Vickers indenter. Statistical evaluation of the data was done using one-way analysis of variance (ANOVA) and the Student’s
t
-test, and the values are tabulated.
Results
Specimens rinsed in 2% CHG showed a significant increase in Vickers hardness number (VHN) values (
p
< 0.05), as compared with EDTA and NaOCl groups, whereas saline and 2% NaF groups showed no significant difference.
Conclusions
NaF did not show any significant effect on microhardness of the root dentin. CHG as an irrigant was seen to have a strengthening effect on dentin microhardness in comparison to NaOCl and EDTA, which has decreased the strength of root dentin.</abstract><cop>A-12, Second Floor, Sector -2, NOIDA -201301, India</cop><pub>Thieme Medical and Scientific Publishers Private Ltd</pub><pmid>33032334</pmid><doi>10.1055/s-0040-1717053</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-7957-3463</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | European journal of dentistry, 2021-05, Vol.15 (2), p.253-258 |
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| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Thieme Connect Journals Open Access |
| subjects | Original Original Article |
| title | Evaluation of 2% Chlorhexidine and 2% Sodium Fluoride as Endodontic Irrigating Solutions on Root Dentine Microhardness: An In Vitro Study |
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