Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer

Purpose Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) have been reported to play an imported role in human cancers, but their role in cervical cancer has not yet been clarified. In this study, we evaluated the functional role of FOXO1 in cervical cancer cells and investigated the expr...

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Veröffentlicht in:	International journal of clinical oncology 2019-11, Vol.24 (11), p.1429-1439
Hauptverfasser:	Chay, Doo Byung, Han, Gwan Hee, Nam, Sanghee, Cho, Hanbyoul, Chung, Joon-Yong, Hewitt, Stephen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cancer Research Cell Line, Tumor Cell migration Cell Movement - genetics Cell Survival - genetics Cell viability Cervical cancer Cervical Intraepithelial Neoplasia - genetics Cervical Intraepithelial Neoplasia - pathology Cervix DNA microarrays Female Forkhead Box Protein O1 - genetics Forkhead Box Protein O1 - metabolism Forkhead protein FOXO1 protein Gene Expression Regulation, Neoplastic Human papillomavirus Humans Kaplan-Meier Estimate Medical prognosis Medicine Medicine & Public Health Middle Aged Multivariate analysis Oncology Original Article Pax3 protein PAX3 Transcription Factor - genetics PAX3 Transcription Factor - metabolism Prognosis Proportional Hazards Models Surgical Oncology Tumor Stem Cell Assay Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - mortality
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