Precision targeting of bacterial pathogen via bi-functional nanozyme activated by biofilm microenvironment

Human dental caries is an intractable biofilm-associated disease caused by microbial interactions and dietary sugars on the host's teeth. Commensal bacteria help control opportunistic pathogens via bioactive products such as hydrogen peroxide (H2O2). However, high-sugar consumption disrupts hom...

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Veröffentlicht in:	Biomaterials 2021-01, Vol.268, p.120581-120581, Article 120581
Hauptverfasser:	Huang, Yue, Liu, Yuan, Shah, Shrey, Kim, Dongyeop, Simon-Soro, Aurea, Ito, Tatsuro, Hajfathalian, Maryam, Li, Yong, Hsu, Jessica C., Nieves, Lenitza M., Alawi, Faizan, Naha, Pratap C., Cormode, David P., Koo, Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Biofilm Biofilms Catalytic nanoparticles Dental caries Dental Caries - drug therapy Glucose oxidase Humans Hybrid nanozyme Hydrogen Peroxide Microbial Interactions Polymicrobial Streptococcus mutans
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