Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review
With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. Howev...
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Veröffentlicht in: | Advances in therapy 2021-07, Vol.38 (7), p.3622-3651 |
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description | With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. However, there is little formal guidance on what intraoperative monitoring techniques should be used in this population. This narrative review collates the existing evidence for intraoperative monitoring devices in the obese patients. Although a number of non-invasive blood pressure monitors have been tested, an invasive arterial line remains the most reliable monitor if accurate, continuous monitoring is required. Goal-directed fluid therapy is recommended by clinical practice guidelines, but the methods tested to assess this had guarded applicability to the obese population. Transcutaneous carbon dioxide (CO
2
) monitoring may offer additional benefit to standard capnography in this population. Individually titrated positive end expiratory pressure (PEEP) and recruitment manoeuvres improved intraoperative mechanics but yielded no benefit in the immediate postoperative period. Depth of anaesthesia monitoring appears to be beneficial in the perioperative period regarding recovery times and complications. Objective confirmation of reversal of neuromuscular blockade continues to be a central tenet of anaesthesia practice, particularly relevant to this group who have been characterised as an “at risk” extubation group. Where deep neuromuscular blockade is used, continuous neuromuscular blockade is suggested. Both obesity and the intraoperative context represent somewhat unstable search terms, as the clinical implications of the obesity phenotype are not uniform, and the type and urgency of surgery have significant impact on the intraoperative setting. This renders the generation of summary conclusions around what intraoperative monitoring techniques are suitable in this population highly challenging. |
doi_str_mv | 10.1007/s12325-021-01774-y |
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2
) monitoring may offer additional benefit to standard capnography in this population. Individually titrated positive end expiratory pressure (PEEP) and recruitment manoeuvres improved intraoperative mechanics but yielded no benefit in the immediate postoperative period. Depth of anaesthesia monitoring appears to be beneficial in the perioperative period regarding recovery times and complications. Objective confirmation of reversal of neuromuscular blockade continues to be a central tenet of anaesthesia practice, particularly relevant to this group who have been characterised as an “at risk” extubation group. Where deep neuromuscular blockade is used, continuous neuromuscular blockade is suggested. Both obesity and the intraoperative context represent somewhat unstable search terms, as the clinical implications of the obesity phenotype are not uniform, and the type and urgency of surgery have significant impact on the intraoperative setting. This renders the generation of summary conclusions around what intraoperative monitoring techniques are suitable in this population highly challenging.</description><identifier>ISSN: 0741-238X</identifier><identifier>EISSN: 1865-8652</identifier><identifier>DOI: 10.1007/s12325-021-01774-y</identifier><identifier>PMID: 34091873</identifier><language>eng</language><publisher>Cheshire: Springer Healthcare</publisher><subject>Anesthesia ; Cardiology ; Endocrinology ; Humans ; Internal Medicine ; Medicine ; Medicine & Public Health ; Monitoring, Intraoperative ; Neuromuscular Blockade ; Obesity - complications ; Obesity - epidemiology ; Obesity - surgery ; Oncology ; Pharmacology/Toxicology ; Positive-Pressure Respiration ; Review ; Rheumatology</subject><ispartof>Advances in therapy, 2021-07, Vol.38 (7), p.3622-3651</ispartof><rights>The Author(s) 2021</rights><rights>2021. The Author(s).</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-100cc593f36c76fbffe097ff0806dda765ee0ad1af121edb40a6ade45967367a3</citedby><cites>FETCH-LOGICAL-c446t-100cc593f36c76fbffe097ff0806dda765ee0ad1af121edb40a6ade45967367a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12325-021-01774-y$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12325-021-01774-y$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34091873$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haren, Andrea P.</creatorcontrib><creatorcontrib>Nair, Shrijit</creatorcontrib><creatorcontrib>Pace, Maria C.</creatorcontrib><creatorcontrib>Sansone, Pasquale</creatorcontrib><title>Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review</title><title>Advances in therapy</title><addtitle>Adv Ther</addtitle><addtitle>Adv Ther</addtitle><description>With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. However, there is little formal guidance on what intraoperative monitoring techniques should be used in this population. This narrative review collates the existing evidence for intraoperative monitoring devices in the obese patients. Although a number of non-invasive blood pressure monitors have been tested, an invasive arterial line remains the most reliable monitor if accurate, continuous monitoring is required. Goal-directed fluid therapy is recommended by clinical practice guidelines, but the methods tested to assess this had guarded applicability to the obese population. Transcutaneous carbon dioxide (CO
2
) monitoring may offer additional benefit to standard capnography in this population. Individually titrated positive end expiratory pressure (PEEP) and recruitment manoeuvres improved intraoperative mechanics but yielded no benefit in the immediate postoperative period. Depth of anaesthesia monitoring appears to be beneficial in the perioperative period regarding recovery times and complications. Objective confirmation of reversal of neuromuscular blockade continues to be a central tenet of anaesthesia practice, particularly relevant to this group who have been characterised as an “at risk” extubation group. Where deep neuromuscular blockade is used, continuous neuromuscular blockade is suggested. Both obesity and the intraoperative context represent somewhat unstable search terms, as the clinical implications of the obesity phenotype are not uniform, and the type and urgency of surgery have significant impact on the intraoperative setting. This renders the generation of summary conclusions around what intraoperative monitoring techniques are suitable in this population highly challenging.</description><subject>Anesthesia</subject><subject>Cardiology</subject><subject>Endocrinology</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Monitoring, Intraoperative</subject><subject>Neuromuscular Blockade</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Obesity - surgery</subject><subject>Oncology</subject><subject>Pharmacology/Toxicology</subject><subject>Positive-Pressure Respiration</subject><subject>Review</subject><subject>Rheumatology</subject><issn>0741-238X</issn><issn>1865-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><recordid>eNp9kclOwzAQhi0EgrK8AAeUI5fAeImdcEBCFZvEJqASN8tNxiWojYudFPXtcWlBcOFg-fAv9sxHyD6FIwqgjgNlnGUpMJoCVUqk8zXSo7nM0njYOumBEjRlPH_ZItshvAEwUFm-Sba4gILmivfI4LppvXFT9KatZ5jcuqZuna-bUeJs0r5icj_EgMlDlLFpk0FToR-5hf7U-RH6-UlyltwZv8o_4qzGj12yYc044N7q3iGDi_Pn_lV6c3953T-7SUshZJvGKcoyK7jlslTSDq1FKJS1kIOsKqNkhgimosZSRrEaCjDSVCiyQiouleE75HTZO-2GE6xKXAwz1lNfT4yfa2dq_Vdp6lc9cjOdU1UoELHgcFXg3XuHodWTOpQ4HpsGXRc0y3gOQmWiiFa2tJbeheDR_jxDQS946CUPHXnoLx56HkMHvz_4E_kGEA18aQjTxdLR6zfX-SYu7b_aT97FmS8</recordid><startdate>20210701</startdate><enddate>20210701</enddate><creator>Haren, Andrea P.</creator><creator>Nair, Shrijit</creator><creator>Pace, Maria C.</creator><creator>Sansone, Pasquale</creator><general>Springer Healthcare</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210701</creationdate><title>Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review</title><author>Haren, Andrea P. ; Nair, Shrijit ; Pace, Maria C. ; Sansone, Pasquale</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-100cc593f36c76fbffe097ff0806dda765ee0ad1af121edb40a6ade45967367a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anesthesia</topic><topic>Cardiology</topic><topic>Endocrinology</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Monitoring, Intraoperative</topic><topic>Neuromuscular Blockade</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Obesity - surgery</topic><topic>Oncology</topic><topic>Pharmacology/Toxicology</topic><topic>Positive-Pressure Respiration</topic><topic>Review</topic><topic>Rheumatology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Haren, Andrea P.</creatorcontrib><creatorcontrib>Nair, Shrijit</creatorcontrib><creatorcontrib>Pace, Maria C.</creatorcontrib><creatorcontrib>Sansone, Pasquale</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Advances in therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haren, Andrea P.</au><au>Nair, Shrijit</au><au>Pace, Maria C.</au><au>Sansone, Pasquale</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review</atitle><jtitle>Advances in therapy</jtitle><stitle>Adv Ther</stitle><addtitle>Adv Ther</addtitle><date>2021-07-01</date><risdate>2021</risdate><volume>38</volume><issue>7</issue><spage>3622</spage><epage>3651</epage><pages>3622-3651</pages><issn>0741-238X</issn><eissn>1865-8652</eissn><abstract>With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. However, there is little formal guidance on what intraoperative monitoring techniques should be used in this population. This narrative review collates the existing evidence for intraoperative monitoring devices in the obese patients. Although a number of non-invasive blood pressure monitors have been tested, an invasive arterial line remains the most reliable monitor if accurate, continuous monitoring is required. Goal-directed fluid therapy is recommended by clinical practice guidelines, but the methods tested to assess this had guarded applicability to the obese population. Transcutaneous carbon dioxide (CO
2
) monitoring may offer additional benefit to standard capnography in this population. Individually titrated positive end expiratory pressure (PEEP) and recruitment manoeuvres improved intraoperative mechanics but yielded no benefit in the immediate postoperative period. Depth of anaesthesia monitoring appears to be beneficial in the perioperative period regarding recovery times and complications. Objective confirmation of reversal of neuromuscular blockade continues to be a central tenet of anaesthesia practice, particularly relevant to this group who have been characterised as an “at risk” extubation group. Where deep neuromuscular blockade is used, continuous neuromuscular blockade is suggested. Both obesity and the intraoperative context represent somewhat unstable search terms, as the clinical implications of the obesity phenotype are not uniform, and the type and urgency of surgery have significant impact on the intraoperative setting. This renders the generation of summary conclusions around what intraoperative monitoring techniques are suitable in this population highly challenging.</abstract><cop>Cheshire</cop><pub>Springer Healthcare</pub><pmid>34091873</pmid><doi>10.1007/s12325-021-01774-y</doi><tpages>30</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anesthesia Cardiology Endocrinology Humans Internal Medicine Medicine Medicine & Public Health Monitoring, Intraoperative Neuromuscular Blockade Obesity - complications Obesity - epidemiology Obesity - surgery Oncology Pharmacology/Toxicology Positive-Pressure Respiration Review Rheumatology |
title | Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review |
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