Fine particulate matter and out-of-hospital cardiac arrest of respiratory origin

Exposure to ambient air pollution increases mortality and is a leading contributor to the global disease burden [1]. Epidemiological studies have elucidated a relationship between out-of-hospital cardiac arrests (OHCAs) and air pollutants, especially particulate matter (diameter ≤2.5 μm; PM 2.5 ) [2...

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Veröffentlicht in:The European respiratory journal 2021-06, Vol.57 (6), p.2004299
Hauptverfasser: Kojima, Sunao, Michikawa, Takehiro, Matsui, Kunihiko, Ogawa, Hisao, Yamazaki, Shin, Nitta, Hiroshi, Takami, Akinori, Ueda, Kayo, Tahara, Yoshio, Yonemoto, Naohiro, Nonogi, Hiroshi, Nagao, Ken, Ikeda, Takanori, Kobayashi, Yoshio
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container_issue 6
container_start_page 2004299
container_title The European respiratory journal
container_volume 57
creator Kojima, Sunao
Michikawa, Takehiro
Matsui, Kunihiko
Ogawa, Hisao
Yamazaki, Shin
Nitta, Hiroshi
Takami, Akinori
Ueda, Kayo
Tahara, Yoshio
Yonemoto, Naohiro
Nonogi, Hiroshi
Nagao, Ken
Ikeda, Takanori
Kobayashi, Yoshio
description Exposure to ambient air pollution increases mortality and is a leading contributor to the global disease burden [1]. Epidemiological studies have elucidated a relationship between out-of-hospital cardiac arrests (OHCAs) and air pollutants, especially particulate matter (diameter ≤2.5 μm; PM 2.5 ) [2, 3]. The causes of OHCA are broadly categorised as cardiac and non-cardiac [4]. A 10 µg·m −3 increase in PM 2.5 exposure yielded a 1.6% increase in the incidence of cardiac origin OHCA [3, 5]. However, few studies on OHCAs of non-cardiac origin, including intrinsic respiratory diseases (COPD/pneumonia/asthma) are available. We examined the association between short-term exposure to PM 2.5 and bystander-witnessed respiratory origin OHCAs, including eventual prognosis. We also investigated differences between PM 2.5 exposure-related cardiac and respiratory origin OHCAs. Particulate matter is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. The percent increase in incidence of OHCA of respiratory origin is equivalent to that of PM 2.5 exposure-related OHCAs of cardiac origin. http://bit.ly/3tDXym0
doi_str_mv 10.1183/13993003.04299-2020
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Epidemiological studies have elucidated a relationship between out-of-hospital cardiac arrests (OHCAs) and air pollutants, especially particulate matter (diameter ≤2.5 μm; PM 2.5 ) [2, 3]. The causes of OHCA are broadly categorised as cardiac and non-cardiac [4]. A 10 µg·m −3 increase in PM 2.5 exposure yielded a 1.6% increase in the incidence of cardiac origin OHCA [3, 5]. However, few studies on OHCAs of non-cardiac origin, including intrinsic respiratory diseases (COPD/pneumonia/asthma) are available. We examined the association between short-term exposure to PM 2.5 and bystander-witnessed respiratory origin OHCAs, including eventual prognosis. We also investigated differences between PM 2.5 exposure-related cardiac and respiratory origin OHCAs. Particulate matter is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. 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title Fine particulate matter and out-of-hospital cardiac arrest of respiratory origin
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