Widespread cefiderocol heteroresistance in carbapenem-resistant Gram-negative pathogens

Heteroresistance is a form of antibiotic resistance in which a bacterial isolate harbours a minority resistant subpopulation of cells that coexists with a majority susceptible population, and it is often undetected by standard antimicrobial susceptibility testing (AST; appendix pp 1–2).2 In the pres...

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