Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs

Conventional molecular tests for detecting complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole-genome sequencing (WGS) typically requires culture.Here, we evaluated the Deeplex Myc-TB targeted deep-sequencing assay for prediction of resistance to 13 anti-tuberc...

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Veröffentlicht in:	The European respiratory journal 2021-03, Vol.57 (3), p.2002338
Hauptverfasser:	Jouet, Agathe, Gaudin, Cyril, Badalato, Nelly, Allix-Béguec, Caroline, Duthoy, Stéphanie, Ferré, Alice, Diels, Maren, Laurent, Yannick, Contreras, Sandy, Feuerriegel, Silke, Niemann, Stefan, André, Emmanuel, Kaswa, Michel K, Tagliani, Elisa, Cabibbe, Andrea, Mathys, Vanessa, Cirillo, Daniela, de Jong, Bouke C, Rigouts, Leen, Supply, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Human health and pathology Infectious diseases Life Sciences Microbiology and Parasitology Original Pulmonology and respiratory tract
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