Altered Genes and Biological Functions in Response to Severe Burns

Severe burns are acute wounds caused by local heat exposure, resulting in life-threatening systemic effects and poor survival. However, the specific molecular mechanisms remain unclear. First, we downloaded gene expression data related to severe burns from the GEO database (GSE19743, GSE37069, and G...

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Veröffentlicht in:	BioMed research international 2021-05, Vol.2021, p.1-19
Hauptverfasser:	Liu, Xinheng, Rong, Yongxian, Huang, Donglin, Liang, Zhijie, Yi, Xiaolin, Wu, Fangxiao, Zhu, Dandan, Mo, Steven, Nong, Wenhai, Li, Hongmian
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biomarkers Blood Burn patients Burns Burns and scalds Care and treatment Cell cycle Datasets Development and progression Enrichment Gene expression Gene set enrichment analysis Genes Genetic aspects Immune response Immune system Lck protein Medical prognosis Metabolic response Metabolism Modules Molecular modelling Network analysis Patient outcomes Patients Principal components analysis Protein interaction Protein-protein interactions Proteins Regression analysis Rehabilitation Survival T cell receptors Therapeutic targets Transcription factors Tumor necrosis factor-TNF
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