Upregulation of eIF4E, but not other translation initiation factors, in dendritic spines during memory formation

Local translation can provide a rapid, spatially targeted supply of new proteins in distal dendrites to support synaptic changes that underlie learning. Learning and memory are especially sensitive to manipulations of translational control mechanisms, particularly those that target the initiation st...

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Veröffentlicht in:Journal of comparative neurology (1911) 2021-08, Vol.529 (11), p.3112-3126
Hauptverfasser: Gindina, Sofya, Botsford, Benjamin, Cowansage, Kiriana, LeDoux, Joseph, Klann, Eric, Hoeffer, Charles, Ostroff, Linnaea
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Sprache:eng
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