Phosphatidylethanol in whole blood of rhesus monkeys correlates with ethanol consumption

Background Phosphatidylethanol (PEth) homologs are ethanol metabolites used to identify and monitor alcohol drinking in humans. In this study, we measured levels of the 2 most abundant homologs, PEth 16:0/18:1 and PEth 16:0/18:2, in whole blood samples from rhesus macaque monkeys that drank ethanol...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2021-04, Vol.45 (4), p.689-696
Hauptverfasser:	Lopez‐Cruzan, Marisa, Walter, Nicole A. R., Sanchez, Jesus J., Ginsburg, Brett C., Koek, Wouter, Jimenez, Vanessa A., Grant, Kathleen A., Javors, Martin A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - blood Amino Acid Sequence Animal models Animals blood Central Nervous System Depressants - administration & dosage Conserved Sequence Drinking behavior Ethanol Ethanol - administration & dosage Glycerophospholipids - blood High-performance liquid chromatography Humans Macaca mulatta Male Mass spectroscopy Monkeys & apes phosphatidylethanol (PEth) phospholipase D (PLD) Phospholipase D - chemistry rhesus monkey
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