Interplay of the ubiquitin proteasome system and the innate immune response is essential for the replication of infectious bronchitis virus

Infectious bronchitis virus (IBV) is the only coronavirus known to infect poultry. The replication and pathogenesis of IBV are poorly understood, mainly because of the unavailability of a robust cell culture system. Here, we report that an active ubiquitin proteasome system (UPS) is necessary for ef...

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