A Retrospective Study Supporting the Importance of Individualizing the Dose of Botulinum Toxin According to the Age
Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide with a high rate of efficacy and patient satisfaction. This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patient...
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| Veröffentlicht in: | Journal of cutaneous and aesthetic surgery 2021-01, Vol.14 (1), p.88-92 |
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| container_title | Journal of cutaneous and aesthetic surgery |
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| creator | Bravo, Bruna Souza Felix Carvalho, Raquel de Melo Gallo, Bruna Fanton Bravo, Leonardo Gonçalves |
| description | Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide with a high rate of efficacy and patient satisfaction.
This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patients, considering the muscles particularities and the specificities of each face area.
A retrospective study with 389 female patients treated with botulinum toxin type A in the upper third of the face (forehead, glabellar, and periorbital lines). Statistical analysis of the data was performed.
The mean age was 47.49 years old and the median total dose of botulinum toxin type A was 53.76 units, whereas the median dose in the glabella was 26.28 U, the mean forehead dose was 12.23 U, and in the periorbital area was 14.79 U, adding both sides. It is possible to observe that the doses are negatively correlated with age, except in the periorbital area, where an increase in the dose was observed.
It is important to highlight that although there is consensus on pre-established dose suggestions, the treatment should be individualized, respecting the individual characteristics of each patient. |
| doi_str_mv | 10.4103/JCAS.JCAS_20_20 |
| format | Article |
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This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patients, considering the muscles particularities and the specificities of each face area.
A retrospective study with 389 female patients treated with botulinum toxin type A in the upper third of the face (forehead, glabellar, and periorbital lines). Statistical analysis of the data was performed.
The mean age was 47.49 years old and the median total dose of botulinum toxin type A was 53.76 units, whereas the median dose in the glabella was 26.28 U, the mean forehead dose was 12.23 U, and in the periorbital area was 14.79 U, adding both sides. It is possible to observe that the doses are negatively correlated with age, except in the periorbital area, where an increase in the dose was observed.
It is important to highlight that although there is consensus on pre-established dose suggestions, the treatment should be individualized, respecting the individual characteristics of each patient.</description><identifier>ISSN: 0974-2077</identifier><identifier>EISSN: 0974-5157</identifier><identifier>DOI: 10.4103/JCAS.JCAS_20_20</identifier><identifier>PMID: 34084014</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Analysis ; Botulinum toxin ; Medical research ; Medicine, Experimental ; Original ; Patient satisfaction ; Pharmaceutical industry</subject><ispartof>Journal of cutaneous and aesthetic surgery, 2021-01, Vol.14 (1), p.88-92</ispartof><rights>Copyright: © 2021 Journal of Cutaneous and Aesthetic Surgery.</rights><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright: © 2021 Journal of Cutaneous and Aesthetic Surgery 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3360-2b9b95135f2e9856107aa7c269f7fa5efc616e5092ffaff946592c60f79a1f393</citedby><cites>FETCH-LOGICAL-c3360-2b9b95135f2e9856107aa7c269f7fa5efc616e5092ffaff946592c60f79a1f393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149977/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149977/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,4024,27923,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34084014$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bravo, Bruna Souza Felix</creatorcontrib><creatorcontrib>Carvalho, Raquel de Melo</creatorcontrib><creatorcontrib>Gallo, Bruna Fanton</creatorcontrib><creatorcontrib>Bravo, Leonardo Gonçalves</creatorcontrib><title>A Retrospective Study Supporting the Importance of Individualizing the Dose of Botulinum Toxin According to the Age</title><title>Journal of cutaneous and aesthetic surgery</title><addtitle>J Cutan Aesthet Surg</addtitle><description>Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide with a high rate of efficacy and patient satisfaction.
This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patients, considering the muscles particularities and the specificities of each face area.
A retrospective study with 389 female patients treated with botulinum toxin type A in the upper third of the face (forehead, glabellar, and periorbital lines). Statistical analysis of the data was performed.
The mean age was 47.49 years old and the median total dose of botulinum toxin type A was 53.76 units, whereas the median dose in the glabella was 26.28 U, the mean forehead dose was 12.23 U, and in the periorbital area was 14.79 U, adding both sides. It is possible to observe that the doses are negatively correlated with age, except in the periorbital area, where an increase in the dose was observed.
It is important to highlight that although there is consensus on pre-established dose suggestions, the treatment should be individualized, respecting the individual characteristics of each patient.</description><subject>Analysis</subject><subject>Botulinum toxin</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Original</subject><subject>Patient satisfaction</subject><subject>Pharmaceutical industry</subject><issn>0974-2077</issn><issn>0974-5157</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNptkl1v0zAUhiMEYtPYNXcoEhLipp0_4_gGKZQBRZOQ6Li2XOe4NUrsEDsV268nabuxStiWP855zivZfrPsNUZzhhG9-raoVvNpUgSN41l2jqRgM465eH7cEyTEWXYZ4y80NkpKJtnL7IwyVDKE2XkWq_wHpD7EDkxyO8hXaajv8tXQdaFPzm_ytIV82U4n7Q3kweZLX7udqwfduPsH4lOI-9zHkIbG-aHNb8Mf5_PKmNDXeyrswWoDr7IXVjcRLo_rRfbz8_Xt4uvs5vuX5aK6mRlKCzQja7mWHFNuCciSFxgJrYUhhbTCag7WFLgAjiSxVlsrWcElMQWyQmpsqaQX2YeDbjesW6gN-NTrRnW9a3V_p4J26jTj3VZtwk6VmEkpxCjw_ijQh98DxKRaFw00jfYQhqgIp6KgksgJfXtAN7oB5bwNo6KZcFUJxnEpEOMjNf8PNfYaWmeCB-vG-EnBuycFW9BN2sbQDMkFH0_BqwNoxr-MPdjHa2KkJreovVH-uWWsePP0dR75B2_QvxHCuu4</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Bravo, Bruna Souza Felix</creator><creator>Carvalho, Raquel de Melo</creator><creator>Gallo, Bruna Fanton</creator><creator>Bravo, Leonardo Gonçalves</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202101</creationdate><title>A Retrospective Study Supporting the Importance of Individualizing the Dose of Botulinum Toxin According to the Age</title><author>Bravo, Bruna Souza Felix ; Carvalho, Raquel de Melo ; Gallo, Bruna Fanton ; Bravo, Leonardo Gonçalves</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3360-2b9b95135f2e9856107aa7c269f7fa5efc616e5092ffaff946592c60f79a1f393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Analysis</topic><topic>Botulinum toxin</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Original</topic><topic>Patient satisfaction</topic><topic>Pharmaceutical industry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bravo, Bruna Souza Felix</creatorcontrib><creatorcontrib>Carvalho, Raquel de Melo</creatorcontrib><creatorcontrib>Gallo, Bruna Fanton</creatorcontrib><creatorcontrib>Bravo, Leonardo Gonçalves</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of cutaneous and aesthetic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bravo, Bruna Souza Felix</au><au>Carvalho, Raquel de Melo</au><au>Gallo, Bruna Fanton</au><au>Bravo, Leonardo Gonçalves</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Retrospective Study Supporting the Importance of Individualizing the Dose of Botulinum Toxin According to the Age</atitle><jtitle>Journal of cutaneous and aesthetic surgery</jtitle><addtitle>J Cutan Aesthet Surg</addtitle><date>2021-01</date><risdate>2021</risdate><volume>14</volume><issue>1</issue><spage>88</spage><epage>92</epage><pages>88-92</pages><issn>0974-2077</issn><eissn>0974-5157</eissn><abstract>Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide with a high rate of efficacy and patient satisfaction.
This study aims to demonstrate the importance of individualization of botulinum toxin doses to treat the upper face according to the age of the patients, considering the muscles particularities and the specificities of each face area.
A retrospective study with 389 female patients treated with botulinum toxin type A in the upper third of the face (forehead, glabellar, and periorbital lines). Statistical analysis of the data was performed.
The mean age was 47.49 years old and the median total dose of botulinum toxin type A was 53.76 units, whereas the median dose in the glabella was 26.28 U, the mean forehead dose was 12.23 U, and in the periorbital area was 14.79 U, adding both sides. It is possible to observe that the doses are negatively correlated with age, except in the periorbital area, where an increase in the dose was observed.
It is important to highlight that although there is consensus on pre-established dose suggestions, the treatment should be individualized, respecting the individual characteristics of each patient.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>34084014</pmid><doi>10.4103/JCAS.JCAS_20_20</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; PubMed Central; Medknow Medical Journals (Open access); PubMed Central Open Access |
| subjects | Analysis Botulinum toxin Medical research Medicine, Experimental Original Patient satisfaction Pharmaceutical industry |
| title | A Retrospective Study Supporting the Importance of Individualizing the Dose of Botulinum Toxin According to the Age |
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