Causal Effects of Serum Levels of n-3 or n-6 Polyunsaturated Fatty Acids on Coronary Artery Disease: Mendelian Randomization Study

We aimed to investigate the causal effects of n-3 and n-6 polyunsaturated fatty acids (PUFAs) on the risk of coronary artery disease (CAD) through Mendelian randomization (MR) analysis. This MR study utilized a genetic instrument developed from previous genome-wide association studies for various se...

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Veröffentlicht in:	Nutrients 2021-04, Vol.13 (5), p.1490
Hauptverfasser:	Park, Sehoon, Lee, Soojin, Kim, Yaerim, Lee, Yeonhee, Kang, Minwoo, Kim, Kwangsoo, Kim, Yongchul, Han, Seungseok, Lee, Hajeong, Lee, Jungpyo, Joo, Kwonwook, Lim, Chunsoo, Kim, Yonsu, Kim, Dongki
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Analysis Arachidonic acid Biobanks Cardiovascular disease Cohort Studies Coronary artery Coronary artery disease Coronary Artery Disease - blood Coronary heart disease Coronary vessels Diabetes Disease prevention Eicosapentaenoic acid Essential fatty acids Fatty acids Fatty Acids, Omega-3 - blood Fatty Acids, Omega-6 - blood Female Genome-wide association studies Genomes Genomics Health risks Heart diseases Humans Hypertension Linoleic acid Linolenic acid Lipoproteins Male Medical research Medicine, Experimental Mendelian Randomization Analysis - methods Metabolic disorders Middle Aged Pleiotropy Polyunsaturated fatty acids Randomization Risk Sensitivity analysis Serum levels Triglycerides United Kingdom Unsaturated fatty acids
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