A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma

A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 m...

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Veröffentlicht in:World journal of oncology 2021-06, Vol.12 (2-3), p.67-72
Hauptverfasser: Hamada, Kazu, Itoh, Tohru, Kawaura, Ken, Kuno, Hiroaki, Kamai, Junji, Kobayasi, Rika, Azukisawa, Sadahumi, Kitakata, Hidekazu, Ishisaka, Taishi, Igarashi, Yuta, Kodera, Kumie, Okuno, Tazuo, Morita, Takuro, Himeno, Tarou, Yano, Hiroshi, Higashikawa, Toshihiro, Iritani, Osamu, Iwai, Kunimitsu, Morimoto, Shigeto, Matoba, Munetaka, Okuro, Masashi
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container_end_page 72
container_issue 2-3
container_start_page 67
container_title World journal of oncology
container_volume 12
creator Hamada, Kazu
Itoh, Tohru
Kawaura, Ken
Kuno, Hiroaki
Kamai, Junji
Kobayasi, Rika
Azukisawa, Sadahumi
Kitakata, Hidekazu
Ishisaka, Taishi
Igarashi, Yuta
Kodera, Kumie
Okuno, Tazuo
Morita, Takuro
Himeno, Tarou
Yano, Hiroshi
Higashikawa, Toshihiro
Iritani, Osamu
Iwai, Kunimitsu
Morimoto, Shigeto
Matoba, Munetaka
Okuro, Masashi
description A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 months, the ulcer improved but a moderate stenosis remained. Several factors such as high fraction size, history of chemotherapy, and stress associated with food intake might involve in the development of a radiation-associated ulcer. Opportunities to choose radiotherapy for hepatocellular carcinoma may increase, so we hypothesize that esophageal ulcers might be a complication that should be noted associated with this therapy.
doi_str_mv 10.14740/wjon1370
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title A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma
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