Direct Priming of CD8 + T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation

Vaccinia virus (VACV) was the vaccine used to eradicate smallpox and is being repurposed as a vaccine vector. CD8 T cells are key anti-viral mediators, but require priming to become effector or memory cells. Priming requires an interaction with dendritic cells that are either infected (direct primin...

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Veröffentlicht in:	Journal of virology 2021-04, Vol.95 (10)
Hauptverfasser:	Lin, Leon C W, Croft, Sarah N, Croft, Nathan P, Wong, Yik Chun, Smith, Stewart A, Tang, Swee-Seong, Purcell, Anthony W, Tscharke, David C
Format:	Artikel
Sprache:	eng
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	Volltext
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