Defining steps in RAVE-catalyzed V-ATPase assembly using purified RAVE and V-ATPase subcomplexes

The vacuolar H+-ATPase (V-ATPase) is a highly conserved proton pump responsible for the acidification of intracellular organelles in virtually all eukaryotic cells. V-ATPases are regulated by the rapid and reversible disassembly of the peripheral V1 domain from the integral membrane Vo domain, accom...

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Veröffentlicht in:	The Journal of biological chemistry 2021-01, Vol.296, p.100703-100703, Article 100703
Hauptverfasser:	Jaskolka, Michael C., Tarsio, Maureen, Smardon, Anne M., Khan, Md. Murad, Kane, Patricia M.
Format:	Artikel
Sprache:	eng
Schlagworte:	assembly lysosomal acidification proton pump RAVE regulation vacuolar ATPase vacuole yeast
Online-Zugang:	Volltext
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