High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors

Tyrosine phosphorylation (pTyr) plays a pivotal role in signal transduction and is commonly dysregulated in cancer. As a result, profiling tumor pTyr levels may reveal therapeutic insights critical to combating disease. Existing discovery and targeted mass spectrometry-based methods used to monitor...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2021-05, Vol.81 (9), p.2495-2509
Hauptverfasser:	Stopfer, Lauren E, Flower, Cameron T, Gajadhar, Aaron S, Patel, Bhavin, Gallien, Sebastien, Lopez-Ferrer, Daniel, White, Forest M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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