Efficient Transmicrocatheter Delivery of Functional Fibroblasts with a Bioengineered Collagen Gel-Platinum Microcoil Complex: Toward the Development of Endovascular Cell Therapy for Cerebral Aneurysms

Endoaneurysmal implantation of fibroblasts may promote healing of aneurysms and reduce recanalization after therapeutic embolization. The purpose of our study was to develop a device for delivery of fibroblasts with use of current microcoil technology. Cell carrier devices and cell-free devices were...

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Veröffentlicht in:	American Journal of Neuroradiology 2007-09, Vol.28 (8), p.1586-1593
Hauptverfasser:	Abruzzo, T, Tun, T, Sambanis, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical Engineering Catheterization - instrumentation Cell Death Cell Movement - drug effects Cell Survival - drug effects Cell Transplantation - methods Cells, Cultured Collagen - chemistry Coloring Agents Cross-Linking Reagents - pharmacology DNA - metabolism Electrodiagnosis. Electric activity recording Fibroblasts - metabolism Fibroblasts - physiology Fibroblasts - transplantation Gels - chemistry Glutaral - pharmacology Humans Interventional Intracranial Aneurysm - surgery Investigative techniques, diagnostic techniques (general aspects) Medical sciences Nervous system Neurology Platinum Tetrazolium Salts Thiazoles Vascular diseases and vascular malformations of the nervous system
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