EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis

Erythropoietin-producing hepatocellular receptor A2 (EphA2) is a key member of the receptor tyrosine kinase (RTK) family, while YES Proto-Oncogene 1 (YES1) is a non-receptor tyrosine kinase (nRTK) and annexin A2 (ANXA2) belongs to the calcium-dependent phospholipid-binding protein family annexins. H...

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Veröffentlicht in:	Oncogene 2021-05, Vol.40 (20), p.3610-3623
Hauptverfasser:	Mao, Linfeng, Yuan, Weijie, Cai, Kaimei, Lai, Chen, Huang, Changhao, Xu, Yi, Zhong, Shangwei, Yang, Chen, Wang, Ran, Zeng, Pengwei, Huang, Heyuan, Chen, Zhikang, Chen, Zihua
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 13/1 13/105 13/109 13/51 13/89 14/19 14/32 14/34 631/67/1504/1829 631/67/322 64/60 82/80 Animal models Animals Annexin A2 - genetics Annexin A2 - metabolism Annexins Apoptosis Calcium-binding protein Cancer Cell activation Cell Biology Cell Line, Tumor Cell migration Cell Proliferation Cellular signal transduction Development and progression EphA2 protein Erythropoietin Gastric cancer Gene expression Genetic aspects Health aspects Human Genetics Humans Internal Medicine Medicine Medicine & Public Health Metastases Metastasis Mice Mice, Inbred NOD Mice, SCID Mutants Neoplasm Metastasis Oncology Oncology, Experimental Phospholipids Phosphorylation Protein kinases Protein-tyrosine kinase receptors Proto-Oncogene Proteins c-yes - genetics Proto-Oncogene Proteins c-yes - metabolism Receptor, EphA2 - genetics Receptor, EphA2 - metabolism Signal Transduction Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Survival Rate Xenograft Model Antitumor Assays
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