Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects—influence of segmentation and analysis software

Objectives Quantification of myocardial deformation by feature tracking is of growing interest in cardiovascular magnetic resonance. It allows the assessment of regional myocardial function based on cine images. However, image acquisition, post-processing, and interpretation are not standardized. We...

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Veröffentlicht in:European radiology 2021-06, Vol.31 (6), p.3962-3972
Hauptverfasser: Lim, Carolin, Blaszczyk, Edyta, Riazy, Leili, Wiesemann, Stephanie, Schüler, Johannes, von Knobelsdorff-Brenkenhoff, Florian, Schulz-Menger, Jeanette
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container_end_page 3972
container_issue 6
container_start_page 3962
container_title European radiology
container_volume 31
creator Lim, Carolin
Blaszczyk, Edyta
Riazy, Leili
Wiesemann, Stephanie
Schüler, Johannes
von Knobelsdorff-Brenkenhoff, Florian
Schulz-Menger, Jeanette
description Objectives Quantification of myocardial deformation by feature tracking is of growing interest in cardiovascular magnetic resonance. It allows the assessment of regional myocardial function based on cine images. However, image acquisition, post-processing, and interpretation are not standardized. We aimed to assess the influence of segmentation procedure such as slice selection and different types of analysis software on values and quantification of myocardial strain in healthy adults. Methods Healthy volunteers were retrospectively analyzed. Post-processing was performed using CVI 42 and TomTec. Longitudinal and radial Long axis (LAX) strain were quantified using 4-chamber-view, 3-chamber-view, and 2-chamber-view. Circumferential and radial Short axis (SAX) strain were assessed in basal, midventricular, and apical short-axis views and using full coverage. Global and segmental strain values were compared to each other regarding their post-processing approach and analysis software package. Results We screened healthy volunteers studied at 1.5 or 3.0 T and included 67 (age 44.3 ± 16.3 years, 31 females). Circumferential and radial SAX strain values were different between a full coverage approach vs. three short slices (− 17.6 ± 1.8% vs. − 19.2 ± 2.3% and 29.1 ± 4.8% vs. 34.6 ± 7.1%). Different analysis software calculated significantly different strain values. Within the same vendor, different field strengths (− 17.0 ± 2.1% at 1.5 T vs. − 17.0 ± 1.7% at 3 T, p  = 0.845) did not influence the calculated global longitudinal strain (GLS), and were similar in gender (− 17.4 ± 2.0% in females vs. − 16.6 ± 1.8% in males, p  = 0.098). Circumferential and radial strain were different in females and males (circumferential strain − 18.2 ± 1.7% vs. − 17.1 ± 1.8%, p  = 0.029 and radial strain 30.7 ± 4.7% vs. 27.8 ± 4.6%, p  = 0.047). Conclusions Myocardial deformation assessed by feature tracking depends on segmentation procedure and type of analysis software. Circumferential SAX and radial SAX depend on the number of slices used for feature tracking analysis. As known from other imaging modalities, GLS seems to be the most stable parameter. During follow-up studies, standardized conditions should be warranted. Trial registration Retrospectively registered Key Points • Myocardial deformation assessed by feature tracking depends on the segmentation procedure. • Global myocardial strain values differ significantly among vendors. • Standardization in post-processing using
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It allows the assessment of regional myocardial function based on cine images. However, image acquisition, post-processing, and interpretation are not standardized. We aimed to assess the influence of segmentation procedure such as slice selection and different types of analysis software on values and quantification of myocardial strain in healthy adults. Methods Healthy volunteers were retrospectively analyzed. Post-processing was performed using CVI 42 and TomTec. Longitudinal and radial Long axis (LAX) strain were quantified using 4-chamber-view, 3-chamber-view, and 2-chamber-view. Circumferential and radial Short axis (SAX) strain were assessed in basal, midventricular, and apical short-axis views and using full coverage. Global and segmental strain values were compared to each other regarding their post-processing approach and analysis software package. Results We screened healthy volunteers studied at 1.5 or 3.0 T and included 67 (age 44.3 ± 16.3 years, 31 females). Circumferential and radial SAX strain values were different between a full coverage approach vs. three short slices (− 17.6 ± 1.8% vs. − 19.2 ± 2.3% and 29.1 ± 4.8% vs. 34.6 ± 7.1%). Different analysis software calculated significantly different strain values. Within the same vendor, different field strengths (− 17.0 ± 2.1% at 1.5 T vs. − 17.0 ± 1.7% at 3 T, p  = 0.845) did not influence the calculated global longitudinal strain (GLS), and were similar in gender (− 17.4 ± 2.0% in females vs. − 16.6 ± 1.8% in males, p  = 0.098). Circumferential and radial strain were different in females and males (circumferential strain − 18.2 ± 1.7% vs. − 17.1 ± 1.8%, p  = 0.029 and radial strain 30.7 ± 4.7% vs. 27.8 ± 4.6%, p  = 0.047). Conclusions Myocardial deformation assessed by feature tracking depends on segmentation procedure and type of analysis software. Circumferential SAX and radial SAX depend on the number of slices used for feature tracking analysis. As known from other imaging modalities, GLS seems to be the most stable parameter. During follow-up studies, standardized conditions should be warranted. Trial registration Retrospectively registered Key Points • Myocardial deformation assessed by feature tracking depends on the segmentation procedure. • Global myocardial strain values differ significantly among vendors. • Standardization in post-processing using CMR feature tracking is essential.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-020-07539-5</identifier><identifier>PMID: 33277669</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Cardiac ; Cardiology ; Chambers ; Circumferences ; Computer programs ; Deformation ; Diagnostic Radiology ; Ejection fraction ; Females ; Image acquisition ; Image segmentation ; Imaging ; Internal Medicine ; Interventional Radiology ; Magnetic resonance ; Males ; Mathematical analysis ; Medicine ; Medicine &amp; Public Health ; Neuroradiology ; Post-production processing ; Radiology ; Resonance ; Software ; Standardization ; Tracking ; Ultrasound</subject><ispartof>European radiology, 2021-06, Vol.31 (6), p.3962-3972</ispartof><rights>The Author(s) 2020</rights><rights>The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-fb99537de3c355a818d88e26a194208ddecf8e30049a083c8b28c9da22cedc473</citedby><cites>FETCH-LOGICAL-c540t-fb99537de3c355a818d88e26a194208ddecf8e30049a083c8b28c9da22cedc473</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-020-07539-5$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-020-07539-5$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33277669$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lim, Carolin</creatorcontrib><creatorcontrib>Blaszczyk, Edyta</creatorcontrib><creatorcontrib>Riazy, Leili</creatorcontrib><creatorcontrib>Wiesemann, Stephanie</creatorcontrib><creatorcontrib>Schüler, Johannes</creatorcontrib><creatorcontrib>von Knobelsdorff-Brenkenhoff, Florian</creatorcontrib><creatorcontrib>Schulz-Menger, Jeanette</creatorcontrib><title>Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects—influence of segmentation and analysis software</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives Quantification of myocardial deformation by feature tracking is of growing interest in cardiovascular magnetic resonance. It allows the assessment of regional myocardial function based on cine images. However, image acquisition, post-processing, and interpretation are not standardized. We aimed to assess the influence of segmentation procedure such as slice selection and different types of analysis software on values and quantification of myocardial strain in healthy adults. Methods Healthy volunteers were retrospectively analyzed. Post-processing was performed using CVI 42 and TomTec. Longitudinal and radial Long axis (LAX) strain were quantified using 4-chamber-view, 3-chamber-view, and 2-chamber-view. Circumferential and radial Short axis (SAX) strain were assessed in basal, midventricular, and apical short-axis views and using full coverage. Global and segmental strain values were compared to each other regarding their post-processing approach and analysis software package. Results We screened healthy volunteers studied at 1.5 or 3.0 T and included 67 (age 44.3 ± 16.3 years, 31 females). Circumferential and radial SAX strain values were different between a full coverage approach vs. three short slices (− 17.6 ± 1.8% vs. − 19.2 ± 2.3% and 29.1 ± 4.8% vs. 34.6 ± 7.1%). Different analysis software calculated significantly different strain values. Within the same vendor, different field strengths (− 17.0 ± 2.1% at 1.5 T vs. − 17.0 ± 1.7% at 3 T, p  = 0.845) did not influence the calculated global longitudinal strain (GLS), and were similar in gender (− 17.4 ± 2.0% in females vs. − 16.6 ± 1.8% in males, p  = 0.098). Circumferential and radial strain were different in females and males (circumferential strain − 18.2 ± 1.7% vs. − 17.1 ± 1.8%, p  = 0.029 and radial strain 30.7 ± 4.7% vs. 27.8 ± 4.6%, p  = 0.047). Conclusions Myocardial deformation assessed by feature tracking depends on segmentation procedure and type of analysis software. Circumferential SAX and radial SAX depend on the number of slices used for feature tracking analysis. As known from other imaging modalities, GLS seems to be the most stable parameter. During follow-up studies, standardized conditions should be warranted. 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Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lim, Carolin</au><au>Blaszczyk, Edyta</au><au>Riazy, Leili</au><au>Wiesemann, Stephanie</au><au>Schüler, Johannes</au><au>von Knobelsdorff-Brenkenhoff, Florian</au><au>Schulz-Menger, Jeanette</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects—influence of segmentation and analysis software</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2021-06-01</date><risdate>2021</risdate><volume>31</volume><issue>6</issue><spage>3962</spage><epage>3972</epage><pages>3962-3972</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives Quantification of myocardial deformation by feature tracking is of growing interest in cardiovascular magnetic resonance. It allows the assessment of regional myocardial function based on cine images. However, image acquisition, post-processing, and interpretation are not standardized. We aimed to assess the influence of segmentation procedure such as slice selection and different types of analysis software on values and quantification of myocardial strain in healthy adults. Methods Healthy volunteers were retrospectively analyzed. Post-processing was performed using CVI 42 and TomTec. Longitudinal and radial Long axis (LAX) strain were quantified using 4-chamber-view, 3-chamber-view, and 2-chamber-view. Circumferential and radial Short axis (SAX) strain were assessed in basal, midventricular, and apical short-axis views and using full coverage. Global and segmental strain values were compared to each other regarding their post-processing approach and analysis software package. Results We screened healthy volunteers studied at 1.5 or 3.0 T and included 67 (age 44.3 ± 16.3 years, 31 females). Circumferential and radial SAX strain values were different between a full coverage approach vs. three short slices (− 17.6 ± 1.8% vs. − 19.2 ± 2.3% and 29.1 ± 4.8% vs. 34.6 ± 7.1%). Different analysis software calculated significantly different strain values. Within the same vendor, different field strengths (− 17.0 ± 2.1% at 1.5 T vs. − 17.0 ± 1.7% at 3 T, p  = 0.845) did not influence the calculated global longitudinal strain (GLS), and were similar in gender (− 17.4 ± 2.0% in females vs. − 16.6 ± 1.8% in males, p  = 0.098). Circumferential and radial strain were different in females and males (circumferential strain − 18.2 ± 1.7% vs. − 17.1 ± 1.8%, p  = 0.029 and radial strain 30.7 ± 4.7% vs. 27.8 ± 4.6%, p  = 0.047). Conclusions Myocardial deformation assessed by feature tracking depends on segmentation procedure and type of analysis software. Circumferential SAX and radial SAX depend on the number of slices used for feature tracking analysis. As known from other imaging modalities, GLS seems to be the most stable parameter. During follow-up studies, standardized conditions should be warranted. Trial registration Retrospectively registered Key Points • Myocardial deformation assessed by feature tracking depends on the segmentation procedure. • Global myocardial strain values differ significantly among vendors. • Standardization in post-processing using CMR feature tracking is essential.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>33277669</pmid><doi>10.1007/s00330-020-07539-5</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record>
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subjects Cardiac
Cardiology
Chambers
Circumferences
Computer programs
Deformation
Diagnostic Radiology
Ejection fraction
Females
Image acquisition
Image segmentation
Imaging
Internal Medicine
Interventional Radiology
Magnetic resonance
Males
Mathematical analysis
Medicine
Medicine & Public Health
Neuroradiology
Post-production processing
Radiology
Resonance
Software
Standardization
Tracking
Ultrasound
title Quantification of myocardial strain assessed by cardiovascular magnetic resonance feature tracking in healthy subjects—influence of segmentation and analysis software
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