In vitro assessment of antitumor immune responses using tumor antigen proteins produced by transgenic silkworms

The evaluation of antitumor immune responses is essential for immune monitoring to predict clinical outcomes as well as treatment efficacies in cancer patients. In this study, we produced two tumor antigen (TA) proteins, melanoma antigen family A4 and wild type p53, using TG silkworm systems and eva...

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Veröffentlicht in:	Journal of materials science. Materials in medicine 2021-06, Vol.32 (6), p.58-58, Article 58
Hauptverfasser:	Yamada, Kanae, Masuda, Kei, Ida, Shota, Tada, Hiroe, Bando, Minori, Abe, Kanako, Tatematsu, Ken-ichiro, Sezutsu, Hideki, Oyama, Tetsunari, Chikamatsu, Kazuaki, Takeda, Shigeki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Animals, Genetically Modified Antigens Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - chemistry Antitumor activity Biocompatibility Studies Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Bombyx Cancer Ceramics Chemistry and Materials Science Composites Evaluation Female Glass Head & neck cancer Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - immunology Head and Neck Neoplasms - therapy Humans Immune response Immune System Immunity Immunohistochemistry Immunotherapy - methods In Vitro Techniques Kaplan-Meier Estimate Leukocytes, Mononuclear - cytology Male Materials Science Medical prognosis Melanoma Middle Aged Natural Materials Neoplasm Proteins - biosynthesis p53 Protein Patients Polymer Sciences Progression-Free Survival Proteins Regenerative Medicine/Tissue Engineering Silkworms Surfaces and Interfaces Survival Systems analysis Thin Films Tumor cells Tumor Suppressor Protein p53 - biosynthesis γ-Interferon
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