D-lactic acidosis presenting as metabolic encephalopathy in a patient with short bowel syndrome
We present a case of D-lactic acidosis presenting as a metabolic encephalopathy secondary to small intestinal bacterial overgrowth. This patient had a known history of short bowel syndrome. Of note, this case required the alteration of treatment to promote a sustained clinical and biochemical improv...
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| Veröffentlicht in: | BMJ case reports 2021-05, Vol.14 (5), p.e241102 |
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| creator | McHale, Ciarán Keating, Eoin O'Donovan, Helen Slattery, Eoin |
| description | We present a case of D-lactic acidosis presenting as a metabolic encephalopathy secondary to small intestinal bacterial overgrowth. This patient had a known history of short bowel syndrome. Of note, this case required the alteration of treatment to promote a sustained clinical and biochemical improvement. We discuss the pathophysiological mechanisms thought to be involved. We also review the current therapies as well as potential future strategies. This case highlights the importance of the prompt clinical recognition of signs and symptoms as well as the rapid initiation of management strategies to ameliorate this condition. |
| doi_str_mv | 10.1136/bcr-2020-241102 |
| format | Article |
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This patient had a known history of short bowel syndrome. Of note, this case required the alteration of treatment to promote a sustained clinical and biochemical improvement. We discuss the pathophysiological mechanisms thought to be involved. We also review the current therapies as well as potential future strategies. This case highlights the importance of the prompt clinical recognition of signs and symptoms as well as the rapid initiation of management strategies to ameliorate this condition.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-241102</identifier><identifier>PMID: 33986009</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Acidosis ; Acidosis, Lactic - diagnosis ; Acidosis, Lactic - etiology ; Antibiotics ; Bioavailability ; Brain Diseases, Metabolic - diagnosis ; Brain Diseases, Metabolic - etiology ; Carbohydrates ; Case Report ; Case reports ; Electrolytes ; Humans ; Intensive care ; Laboratories ; Metabolism ; Metabolites ; Patients ; Short Bowel Syndrome - complications ; Short Bowel Syndrome - therapy ; Small intestine ; Vitamin deficiency</subject><ispartof>BMJ case reports, 2021-05, Vol.14 (5), p.e241102</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. 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This patient had a known history of short bowel syndrome. Of note, this case required the alteration of treatment to promote a sustained clinical and biochemical improvement. We discuss the pathophysiological mechanisms thought to be involved. We also review the current therapies as well as potential future strategies. 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| subjects | Acidosis Acidosis, Lactic - diagnosis Acidosis, Lactic - etiology Antibiotics Bioavailability Brain Diseases, Metabolic - diagnosis Brain Diseases, Metabolic - etiology Carbohydrates Case Report Case reports Electrolytes Humans Intensive care Laboratories Metabolism Metabolites Patients Short Bowel Syndrome - complications Short Bowel Syndrome - therapy Small intestine Vitamin deficiency |
| title | D-lactic acidosis presenting as metabolic encephalopathy in a patient with short bowel syndrome |
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