The Ubiquitin Proteasome System in Genome Stability and Cancer

Faithful DNA replication during cellular division is essential to maintain genome stability and cells have developed a sophisticated network of regulatory systems to ensure its integrity. Disruption of these control mechanisms can lead to loss of genomic stability, a key hallmark of cancer. Ubiquiti...

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Veröffentlicht in:	Cancers 2021-05, Vol.13 (9), p.2235
Hauptverfasser:	Morgan, Jonathan J, Crawford, Lisa J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell cycle Deoxyribonucleic acid DNA DNA biosynthesis DNA damage DNA repair Enzymes Genomes Genomic instability Kinases Post-translation Proteasomes Proteins Regulation Replication Review Therapeutic applications Translation Tumors Ubiquitin Ubiquitination
Online-Zugang:	Volltext
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