Clear-cell variant of oral squamous cell carcinoma: A rare entity

Clear-cell variant of oral squamous cell carcinoma: A rare entity

Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. His...

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Veröffentlicht in:Journal of oral and maxillofacial pathology : JOMFP 2021-03, Vol.25 (4), p.22-26
Hauptverfasser: Ramani, Pratibha, Gheena, S, Karunagaran, Monika, Hannah, R
Format: Artikel
Sprache:eng
Schlagworte:
Actin
Alveoli
Case Report
Case reports
Clear cells
Cytokeratin
Epithelium
Immunohistochemistry
Keratin
Malignancy
Maxillofacial
Mucosa
Oral cancer
Oral squamous cell carcinoma
Smooth muscle
Squamous cell carcinoma
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container_issue 4
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container_title Journal of oral and maxillofacial pathology : JOMFP
container_volume 25
creator Ramani, Pratibha
Gheena, S
Karunagaran, Monika
Hannah, R
description Clear-cell variant of oral squamous cell carcinoma is an extremely rare entity in the maxillofacial region. We report a case of 42-year-old female who presented with a soft-tissue growth with erythematous and nonscrapable irregular white patches on the left alveolar mucosa for the past 3 months. Histopathologic examination showed lobules and sheets of clear cells with features of malignancy extending from the surface epithelium. Periodic acid-Schiff and mucicarmine stains showed a negative reaction. Immunohistochemical study using antibody for pan-cytokeratin revealed intense positivity and negative for the markers such as S-100, smooth muscle actin and CD 117.
doi_str_mv 10.4103/jomfp.JOMFP_295_20
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subjects Actin
Alveoli
Case Report
Case reports
Clear cells
Cytokeratin
Epithelium
Immunohistochemistry
Keratin
Malignancy
Maxillofacial
Mucosa
Oral cancer
Oral squamous cell carcinoma
Smooth muscle
Squamous cell carcinoma
title Clear-cell variant of oral squamous cell carcinoma: A rare entity
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