Copper-Coated Polypropylene Filter Face Mask with SARS-CoV-2 Antiviral Ability
Face masks will be used to prevent pandemic recurrence and outbreaks of mutant SARS-CoV-2 strains until mass immunity is confirmed. The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a...
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| Veröffentlicht in: | Polymers 2021-04, Vol.13 (9), p.1367 |
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| creator | Jung, Sunghoon Yang, Jun-Yeoung Byeon, Eun-Yeon Kim, Do-Geun Lee, Da-Gyum Ryoo, Sungweon Lee, Sanggu Shin, Cheol-Woong Jang, Ho Won Kim, Hyo Jung Lee, Seunghun |
| description | Face masks will be used to prevent pandemic recurrence and outbreaks of mutant SARS-CoV-2 strains until mass immunity is confirmed. The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a copper thin film (20 nm) was deposited via vacuum coating on a spunbond PP filter surrounding a KF94 face mask to provide additional protection and lower the risk of secondary transmission. Film adhesion was improved using oxygen ion beam pretreatment, resulting in cuprous oxide formation on the PP fiber without structural deformation. The copper-coated mask exhibited filtration efficiencies of 95.1 ± 1.32% and 91.6 ± 0.83% for NaCl and paraffin oil particles, respectively. SARS-CoV-2 inactivation was evaluated by transferring virus-containing media onto the copper-coated PP filters and subsequently adding Vero cells. Infection was verified using real-time polymerase chain reaction and immunochemical staining. Vero cells added after contact with the copper-coated mask did not express the RNA-dependent RNA polymerase and envelope genes of SARS-CoV-2. The SARS-CoV-2 nucleocapsid immunofluorescence results indicated a reduction in the amount of virus of more than 75%. Therefore, copper-coated antiviral PP filters could be key materials in personal protective equipment, as well as in air-conditioning systems. |
| doi_str_mv | 10.3390/polym13091367 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8122733</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2520874141</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-fcdffeea39ab42b7f146f5b4a4d5ebc6c32efe9be075adbdd77f7ba44acc94d43</originalsourceid><addsrcrecordid>eNpdkctLAzEQxoMoKurRqyx48bKa1266F6EUq4IvfF1Dkp3Y6HazJttK_3tTrKLOZQbmNx_f8CG0T_AxYxU-6XyzmBKGK8JKsYa2KRYs56zE67_mLbQX4ytOxYuyJGITbaVjStPNNroZ-a6DkI-86qHO7pJgF3y3aKCFbOyaHkI2VgayaxXfsg_XT7KH4f1D4p9zmg3b3s1dUE021K5x_WIXbVjVRNhb9R30ND57HF3kV7fnl6PhVW44KfrcmtpaAMUqpTnVwhJe2kJzxesCtCkNo2Ch0oBFoWpd10JYoRXnypiK15ztoNMv3W6mp1AbaPvkQnbBTVVYSK-c_Ltp3US--LkcEEoFY0ngaCUQ_PsMYi-nLhpoGtWCn0VJC4oHghNOEnr4D331s9Cm9xLFMGFC4KWj_IsywccYwP6YIVguw5J_wkr8we8PfujvaNgnT5KRwg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2530137704</pqid></control><display><type>article</type><title>Copper-Coated Polypropylene Filter Face Mask with SARS-CoV-2 Antiviral Ability</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Jung, Sunghoon ; Yang, Jun-Yeoung ; Byeon, Eun-Yeon ; Kim, Do-Geun ; Lee, Da-Gyum ; Ryoo, Sungweon ; Lee, Sanggu ; Shin, Cheol-Woong ; Jang, Ho Won ; Kim, Hyo Jung ; Lee, Seunghun</creator><creatorcontrib>Jung, Sunghoon ; Yang, Jun-Yeoung ; Byeon, Eun-Yeon ; Kim, Do-Geun ; Lee, Da-Gyum ; Ryoo, Sungweon ; Lee, Sanggu ; Shin, Cheol-Woong ; Jang, Ho Won ; Kim, Hyo Jung ; Lee, Seunghun</creatorcontrib><description>Face masks will be used to prevent pandemic recurrence and outbreaks of mutant SARS-CoV-2 strains until mass immunity is confirmed. The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a copper thin film (20 nm) was deposited via vacuum coating on a spunbond PP filter surrounding a KF94 face mask to provide additional protection and lower the risk of secondary transmission. Film adhesion was improved using oxygen ion beam pretreatment, resulting in cuprous oxide formation on the PP fiber without structural deformation. The copper-coated mask exhibited filtration efficiencies of 95.1 ± 1.32% and 91.6 ± 0.83% for NaCl and paraffin oil particles, respectively. SARS-CoV-2 inactivation was evaluated by transferring virus-containing media onto the copper-coated PP filters and subsequently adding Vero cells. Infection was verified using real-time polymerase chain reaction and immunochemical staining. Vero cells added after contact with the copper-coated mask did not express the RNA-dependent RNA polymerase and envelope genes of SARS-CoV-2. The SARS-CoV-2 nucleocapsid immunofluorescence results indicated a reduction in the amount of virus of more than 75%. Therefore, copper-coated antiviral PP filters could be key materials in personal protective equipment, as well as in air-conditioning systems.</description><identifier>ISSN: 2073-4360</identifier><identifier>EISSN: 2073-4360</identifier><identifier>DOI: 10.3390/polym13091367</identifier><identifier>PMID: 33922136</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Aerosols ; Air conditioning ; Bioaerosols ; Coated masks ; Copper ; Copper oxides ; Coronaviruses ; COVID-19 ; Disease transmission ; Efficiency ; Immunofluorescence ; Infections ; Ion beams ; Masks ; Oxygen ions ; Pandemics ; Paraffins ; Personal protective equipment ; Polymerase chain reaction ; Polymers ; Polypropylene ; Pretreatment ; Ribonucleic acid ; RNA ; Scanning electron microscopy ; Severe acute respiratory syndrome coronavirus 2 ; Spectrum analysis ; Thin films ; Viral diseases ; Viral infections ; Viruses</subject><ispartof>Polymers, 2021-04, Vol.13 (9), p.1367</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-fcdffeea39ab42b7f146f5b4a4d5ebc6c32efe9be075adbdd77f7ba44acc94d43</citedby><cites>FETCH-LOGICAL-c415t-fcdffeea39ab42b7f146f5b4a4d5ebc6c32efe9be075adbdd77f7ba44acc94d43</cites><orcidid>0000-0002-5085-0068 ; 0000-0001-7751-4534 ; 0000-0002-1356-2331 ; 0000-0002-6952-7359</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122733/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122733/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33922136$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, Sunghoon</creatorcontrib><creatorcontrib>Yang, Jun-Yeoung</creatorcontrib><creatorcontrib>Byeon, Eun-Yeon</creatorcontrib><creatorcontrib>Kim, Do-Geun</creatorcontrib><creatorcontrib>Lee, Da-Gyum</creatorcontrib><creatorcontrib>Ryoo, Sungweon</creatorcontrib><creatorcontrib>Lee, Sanggu</creatorcontrib><creatorcontrib>Shin, Cheol-Woong</creatorcontrib><creatorcontrib>Jang, Ho Won</creatorcontrib><creatorcontrib>Kim, Hyo Jung</creatorcontrib><creatorcontrib>Lee, Seunghun</creatorcontrib><title>Copper-Coated Polypropylene Filter Face Mask with SARS-CoV-2 Antiviral Ability</title><title>Polymers</title><addtitle>Polymers (Basel)</addtitle><description>Face masks will be used to prevent pandemic recurrence and outbreaks of mutant SARS-CoV-2 strains until mass immunity is confirmed. The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a copper thin film (20 nm) was deposited via vacuum coating on a spunbond PP filter surrounding a KF94 face mask to provide additional protection and lower the risk of secondary transmission. Film adhesion was improved using oxygen ion beam pretreatment, resulting in cuprous oxide formation on the PP fiber without structural deformation. The copper-coated mask exhibited filtration efficiencies of 95.1 ± 1.32% and 91.6 ± 0.83% for NaCl and paraffin oil particles, respectively. SARS-CoV-2 inactivation was evaluated by transferring virus-containing media onto the copper-coated PP filters and subsequently adding Vero cells. Infection was verified using real-time polymerase chain reaction and immunochemical staining. Vero cells added after contact with the copper-coated mask did not express the RNA-dependent RNA polymerase and envelope genes of SARS-CoV-2. The SARS-CoV-2 nucleocapsid immunofluorescence results indicated a reduction in the amount of virus of more than 75%. Therefore, copper-coated antiviral PP filters could be key materials in personal protective equipment, as well as in air-conditioning systems.</description><subject>Aerosols</subject><subject>Air conditioning</subject><subject>Bioaerosols</subject><subject>Coated masks</subject><subject>Copper</subject><subject>Copper oxides</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Disease transmission</subject><subject>Efficiency</subject><subject>Immunofluorescence</subject><subject>Infections</subject><subject>Ion beams</subject><subject>Masks</subject><subject>Oxygen ions</subject><subject>Pandemics</subject><subject>Paraffins</subject><subject>Personal protective equipment</subject><subject>Polymerase chain reaction</subject><subject>Polymers</subject><subject>Polypropylene</subject><subject>Pretreatment</subject><subject>Ribonucleic acid</subject><subject>RNA</subject><subject>Scanning electron microscopy</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Spectrum analysis</subject><subject>Thin films</subject><subject>Viral diseases</subject><subject>Viral infections</subject><subject>Viruses</subject><issn>2073-4360</issn><issn>2073-4360</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkctLAzEQxoMoKurRqyx48bKa1266F6EUq4IvfF1Dkp3Y6HazJttK_3tTrKLOZQbmNx_f8CG0T_AxYxU-6XyzmBKGK8JKsYa2KRYs56zE67_mLbQX4ytOxYuyJGITbaVjStPNNroZ-a6DkI-86qHO7pJgF3y3aKCFbOyaHkI2VgayaxXfsg_XT7KH4f1D4p9zmg3b3s1dUE021K5x_WIXbVjVRNhb9R30ND57HF3kV7fnl6PhVW44KfrcmtpaAMUqpTnVwhJe2kJzxesCtCkNo2Ch0oBFoWpd10JYoRXnypiK15ztoNMv3W6mp1AbaPvkQnbBTVVYSK-c_Ltp3US--LkcEEoFY0ngaCUQ_PsMYi-nLhpoGtWCn0VJC4oHghNOEnr4D331s9Cm9xLFMGFC4KWj_IsywccYwP6YIVguw5J_wkr8we8PfujvaNgnT5KRwg</recordid><startdate>20210422</startdate><enddate>20210422</enddate><creator>Jung, Sunghoon</creator><creator>Yang, Jun-Yeoung</creator><creator>Byeon, Eun-Yeon</creator><creator>Kim, Do-Geun</creator><creator>Lee, Da-Gyum</creator><creator>Ryoo, Sungweon</creator><creator>Lee, Sanggu</creator><creator>Shin, Cheol-Woong</creator><creator>Jang, Ho Won</creator><creator>Kim, Hyo Jung</creator><creator>Lee, Seunghun</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>COVID</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5085-0068</orcidid><orcidid>https://orcid.org/0000-0001-7751-4534</orcidid><orcidid>https://orcid.org/0000-0002-1356-2331</orcidid><orcidid>https://orcid.org/0000-0002-6952-7359</orcidid></search><sort><creationdate>20210422</creationdate><title>Copper-Coated Polypropylene Filter Face Mask with SARS-CoV-2 Antiviral Ability</title><author>Jung, Sunghoon ; 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The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a copper thin film (20 nm) was deposited via vacuum coating on a spunbond PP filter surrounding a KF94 face mask to provide additional protection and lower the risk of secondary transmission. Film adhesion was improved using oxygen ion beam pretreatment, resulting in cuprous oxide formation on the PP fiber without structural deformation. The copper-coated mask exhibited filtration efficiencies of 95.1 ± 1.32% and 91.6 ± 0.83% for NaCl and paraffin oil particles, respectively. SARS-CoV-2 inactivation was evaluated by transferring virus-containing media onto the copper-coated PP filters and subsequently adding Vero cells. Infection was verified using real-time polymerase chain reaction and immunochemical staining. Vero cells added after contact with the copper-coated mask did not express the RNA-dependent RNA polymerase and envelope genes of SARS-CoV-2. The SARS-CoV-2 nucleocapsid immunofluorescence results indicated a reduction in the amount of virus of more than 75%. Therefore, copper-coated antiviral PP filters could be key materials in personal protective equipment, as well as in air-conditioning systems.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33922136</pmid><doi>10.3390/polym13091367</doi><orcidid>https://orcid.org/0000-0002-5085-0068</orcidid><orcidid>https://orcid.org/0000-0001-7751-4534</orcidid><orcidid>https://orcid.org/0000-0002-1356-2331</orcidid><orcidid>https://orcid.org/0000-0002-6952-7359</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Aerosols Air conditioning Bioaerosols Coated masks Copper Copper oxides Coronaviruses COVID-19 Disease transmission Efficiency Immunofluorescence Infections Ion beams Masks Oxygen ions Pandemics Paraffins Personal protective equipment Polymerase chain reaction Polymers Polypropylene Pretreatment Ribonucleic acid RNA Scanning electron microscopy Severe acute respiratory syndrome coronavirus 2 Spectrum analysis Thin films Viral diseases Viral infections Viruses |
| title | Copper-Coated Polypropylene Filter Face Mask with SARS-CoV-2 Antiviral Ability |
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