The role of RAGE in host pathology and crosstalk between RAGE and TLR4 in innate immune signal transduction pathways

Although the innate immune receptor protein, Receptor for Advanced Glycation End products (RAGE), has been extensively studied, there has been renewed interest in RAGE for its potential role in sepsis, along with a host of other inflammatory diseases of chronic, noninfectious origin. In contrast to...

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Veröffentlicht in:	The FASEB journal 2020-12, Vol.34 (12), p.15659-15674
Hauptverfasser:	Prantner, Daniel, Nallar, Shreeram, Vogel, Stefanie N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DAMPs HMGB1 Humans Immunity, Innate - immunology inflammation Inflammation - immunology Receptor for Advanced Glycation End Products - immunology Signal Transduction - immunology Toll-Like Receptor 4 - immunology toll‐like receptors
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