Accelerated Bone Regeneration by Astragaloside IV through Stimulating the Coupling of Osteogenesis and Angiogenesis

Both osteoblasts and preosteoclasts contribute to the coupling of osteogenesis and angiogenesis, regulating bone regeneration. Astragaloside IV (AS-IV), a glycoside of cycloartane-type triterpene derived from the Chinese herb , exhibits various biological activities, including stimulating angiogenes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of biological sciences 2021-01, Vol.17 (7), p.1821-1836
Hauptverfasser:	Wang, Feng, Qian, Huijuan, Kong, Lingchi, Wang, Wenbo, Wang, Xiaoyu, Xu, Ze, Chai, Yimin, Xu, Jia, Kang, Qinglin
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Angiogenesis Animals Antibodies Astragalus membranaceus Biomechanics Biomedical materials Bone growth Bone marrow Bone Marrow - drug effects Bone Marrow - metabolism Bone Regeneration - drug effects Bone Regeneration - physiology Cell activation Cell differentiation Cell Proliferation Cell viability Cells, Cultured Coupling Differentiation (biology) Distraction osteogenesis Drugs, Chinese Herbal Experiments Gene expression Growth factors Hypoxia Ischemia Kinases Male Mesenchyme Models, Animal Neovascularization, Physiologic - physiology Osteoblasts - cytology Osteoblasts - drug effects Osteoclastogenesis Osteogenesis - drug effects Osteogenesis - physiology Phosphatase Platelet-derived growth factor Platelet-derived growth factor BB Rats Rats, Sprague-Dawley Regeneration Regeneration (physiology) Research Paper Saponins - pharmacology Signaling Stem cells Therapeutic targets Triterpenes - pharmacology β-Catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!