Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages
Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheuma...
Gespeichert in:
| Veröffentlicht in: | BMJ case reports 2021-05, Vol.14 (5), p.e240929 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 5 |
| container_start_page | e240929 |
| container_title | BMJ case reports |
| container_volume | 14 |
| creator | Kowitz, Monique Chakradeo, Katrina Hennessey, Ashleigh Wolski, Penny |
| description | Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheumatological disorders in general can contribute to multiple pregnancy complications, very little is known about how anti-SS itself affects pregnancy outcomes. Described here is the case of a 26-year-old pregnant woman with anti-SS whose pregnancy course was complicated by placental dysfunction and subsequent extremely premature delivery at 24 weeks’ gestation. This report presents a review of the literature to date and discusses potential pregnancy complications associated with anti-SS and their subsequent targeted management. |
| doi_str_mv | 10.1136/bcr-2020-240929 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8117991</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2525380901</sourcerecordid><originalsourceid>FETCH-LOGICAL-b456t-49f284196d1df09e254f8ce3bbb76482eb96c1f4f6415cfaa6e425406087fc483</originalsourceid><addsrcrecordid>eNqFkc1rFTEUxYMottSu3UnAjQhj8zWZZCNI8QsKulBwIyHJu3kvj5mkJjN99L83w6ulujGbey_3l8M9HISeU_KGUi4vnC8dI4x0TBDN9CN0Sod-6AZNfjx-0J-g81r3pD1OhRL8KTrhXA-94sMp-vm1wGTnpQAe4w1gF8u8wzFhiw95sgkfYpttmmO9TfMOZlsBt3ZT8gQ45HHMh5i2uIBfSoE04ylWb0uJdgv1GXoS7Fjh_K6eoe8f3n-7_NRdffn4-fLdVedEL-dO6MCUoFpu6CYQDawXQXngzrlBCsXAaelpEEEK2vtgrQTRGCKJGoIXip-ht0fd68VNsPHtjmJHc13iZMutyTaavzcp7sw23xhF6aA1bQKv7gRK_rVAnc1qA8bRJshLNaxnknJFpGzoy3_QfV5KavZWqm-QJqvgxZHyJddaINwfQ4lZ0zMtPbOmZ47ptR8vHnq45_9k1YDXR8BN-_-q_QbBfqTH</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2525380901</pqid></control><display><type>article</type><title>Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Kowitz, Monique ; Chakradeo, Katrina ; Hennessey, Ashleigh ; Wolski, Penny</creator><creatorcontrib>Kowitz, Monique ; Chakradeo, Katrina ; Hennessey, Ashleigh ; Wolski, Penny</creatorcontrib><description>Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheumatological disorders in general can contribute to multiple pregnancy complications, very little is known about how anti-SS itself affects pregnancy outcomes. Described here is the case of a 26-year-old pregnant woman with anti-SS whose pregnancy course was complicated by placental dysfunction and subsequent extremely premature delivery at 24 weeks’ gestation. This report presents a review of the literature to date and discusses potential pregnancy complications associated with anti-SS and their subsequent targeted management.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-240929</identifier><identifier>PMID: 33975837</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Abortion, Habitual ; Adult ; Amino Acyl-tRNA Synthetases ; Antibodies ; Arthritis ; Autoantibodies ; Autoimmune diseases ; Biopsy ; Case Report ; Case reports ; Drug dosages ; Enzymes ; Female ; Histology ; Humans ; Hypertension ; Immunoglobulins ; Live Birth ; Lung diseases ; Miscarriage ; Myositis - complications ; Obstetrics ; Placenta ; Preeclampsia ; Pregnancy ; Premature birth ; Thrombosis ; Ultrasonic imaging ; Veins & arteries ; Womens health</subject><ispartof>BMJ case reports, 2021-05, Vol.14 (5), p.e240929</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b456t-49f284196d1df09e254f8ce3bbb76482eb96c1f4f6415cfaa6e425406087fc483</citedby><cites>FETCH-LOGICAL-b456t-49f284196d1df09e254f8ce3bbb76482eb96c1f4f6415cfaa6e425406087fc483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117991/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117991/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33975837$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kowitz, Monique</creatorcontrib><creatorcontrib>Chakradeo, Katrina</creatorcontrib><creatorcontrib>Hennessey, Ashleigh</creatorcontrib><creatorcontrib>Wolski, Penny</creatorcontrib><title>Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheumatological disorders in general can contribute to multiple pregnancy complications, very little is known about how anti-SS itself affects pregnancy outcomes. Described here is the case of a 26-year-old pregnant woman with anti-SS whose pregnancy course was complicated by placental dysfunction and subsequent extremely premature delivery at 24 weeks’ gestation. This report presents a review of the literature to date and discusses potential pregnancy complications associated with anti-SS and their subsequent targeted management.</description><subject>Abortion, Habitual</subject><subject>Adult</subject><subject>Amino Acyl-tRNA Synthetases</subject><subject>Antibodies</subject><subject>Arthritis</subject><subject>Autoantibodies</subject><subject>Autoimmune diseases</subject><subject>Biopsy</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Drug dosages</subject><subject>Enzymes</subject><subject>Female</subject><subject>Histology</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Immunoglobulins</subject><subject>Live Birth</subject><subject>Lung diseases</subject><subject>Miscarriage</subject><subject>Myositis - complications</subject><subject>Obstetrics</subject><subject>Placenta</subject><subject>Preeclampsia</subject><subject>Pregnancy</subject><subject>Premature birth</subject><subject>Thrombosis</subject><subject>Ultrasonic imaging</subject><subject>Veins & arteries</subject><subject>Womens health</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkc1rFTEUxYMottSu3UnAjQhj8zWZZCNI8QsKulBwIyHJu3kvj5mkJjN99L83w6ulujGbey_3l8M9HISeU_KGUi4vnC8dI4x0TBDN9CN0Sod-6AZNfjx-0J-g81r3pD1OhRL8KTrhXA-94sMp-vm1wGTnpQAe4w1gF8u8wzFhiw95sgkfYpttmmO9TfMOZlsBt3ZT8gQ45HHMh5i2uIBfSoE04ylWb0uJdgv1GXoS7Fjh_K6eoe8f3n-7_NRdffn4-fLdVedEL-dO6MCUoFpu6CYQDawXQXngzrlBCsXAaelpEEEK2vtgrQTRGCKJGoIXip-ht0fd68VNsPHtjmJHc13iZMutyTaavzcp7sw23xhF6aA1bQKv7gRK_rVAnc1qA8bRJshLNaxnknJFpGzoy3_QfV5KavZWqm-QJqvgxZHyJddaINwfQ4lZ0zMtPbOmZ47ptR8vHnq45_9k1YDXR8BN-_-q_QbBfqTH</recordid><startdate>20210511</startdate><enddate>20210511</enddate><creator>Kowitz, Monique</creator><creator>Chakradeo, Katrina</creator><creator>Hennessey, Ashleigh</creator><creator>Wolski, Penny</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210511</creationdate><title>Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages</title><author>Kowitz, Monique ; Chakradeo, Katrina ; Hennessey, Ashleigh ; Wolski, Penny</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b456t-49f284196d1df09e254f8ce3bbb76482eb96c1f4f6415cfaa6e425406087fc483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Abortion, Habitual</topic><topic>Adult</topic><topic>Amino Acyl-tRNA Synthetases</topic><topic>Antibodies</topic><topic>Arthritis</topic><topic>Autoantibodies</topic><topic>Autoimmune diseases</topic><topic>Biopsy</topic><topic>Case Report</topic><topic>Case reports</topic><topic>Drug dosages</topic><topic>Enzymes</topic><topic>Female</topic><topic>Histology</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Immunoglobulins</topic><topic>Live Birth</topic><topic>Lung diseases</topic><topic>Miscarriage</topic><topic>Myositis - complications</topic><topic>Obstetrics</topic><topic>Placenta</topic><topic>Preeclampsia</topic><topic>Pregnancy</topic><topic>Premature birth</topic><topic>Thrombosis</topic><topic>Ultrasonic imaging</topic><topic>Veins & arteries</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kowitz, Monique</creatorcontrib><creatorcontrib>Chakradeo, Katrina</creatorcontrib><creatorcontrib>Hennessey, Ashleigh</creatorcontrib><creatorcontrib>Wolski, Penny</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kowitz, Monique</au><au>Chakradeo, Katrina</au><au>Hennessey, Ashleigh</au><au>Wolski, Penny</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2021-05-11</date><risdate>2021</risdate><volume>14</volume><issue>5</issue><spage>e240929</spage><pages>e240929-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>Antisynthetase syndrome (anti-SS) is a rare systemic autoimmune disease characterised by autoantibodies against aminoacyl-tRNA synthetases manifesting as one or more components of the classic triad: interstitial lung disease, arthritis and myositis. While it is well-recognised that autoimmune rheumatological disorders in general can contribute to multiple pregnancy complications, very little is known about how anti-SS itself affects pregnancy outcomes. Described here is the case of a 26-year-old pregnant woman with anti-SS whose pregnancy course was complicated by placental dysfunction and subsequent extremely premature delivery at 24 weeks’ gestation. This report presents a review of the literature to date and discusses potential pregnancy complications associated with anti-SS and their subsequent targeted management.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>33975837</pmid><doi>10.1136/bcr-2020-240929</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1757-790X |
| ispartof | BMJ case reports, 2021-05, Vol.14 (5), p.e240929 |
| issn | 1757-790X 1757-790X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8117991 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Abortion, Habitual Adult Amino Acyl-tRNA Synthetases Antibodies Arthritis Autoantibodies Autoimmune diseases Biopsy Case Report Case reports Drug dosages Enzymes Female Histology Humans Hypertension Immunoglobulins Live Birth Lung diseases Miscarriage Myositis - complications Obstetrics Placenta Preeclampsia Pregnancy Premature birth Thrombosis Ultrasonic imaging Veins & arteries Womens health |
| title | Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T13%3A03%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Premature%20live%20birth%20in%20a%20woman%20with%20antisynthetase%20syndrome%20following%20recurrent%20miscarriages&rft.jtitle=BMJ%20case%20reports&rft.au=Kowitz,%20Monique&rft.date=2021-05-11&rft.volume=14&rft.issue=5&rft.spage=e240929&rft.pages=e240929-&rft.issn=1757-790X&rft.eissn=1757-790X&rft_id=info:doi/10.1136/bcr-2020-240929&rft_dat=%3Cproquest_pubme%3E2525380901%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2525380901&rft_id=info:pmid/33975837&rfr_iscdi=true |