Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
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| Veröffentlicht in: | Cell research 2021-04, Vol.31 (4), p.478-481 |
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| creator | Li, Mengqi Zhang, Chen-Song Feng, Jin-Wei Wei, Xiaoyan Zhang, Cixiong Xie, Changchuan Wu, Yaying Hawley, Simon A. Atrih, Abdelmadjid Lamont, Douglas J. Wang, Zhichao Piao, Hai-Long Hardie, D. Grahame Lin, Sheng-Cai |
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| doi_str_mv | 10.1038/s41422-020-00456-8 |
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Grahame ; Lin, Sheng-Cai</creatorcontrib><identifier>ISSN: 1001-0602</identifier><identifier>EISSN: 1748-7838</identifier><identifier>DOI: 10.1038/s41422-020-00456-8</identifier><identifier>PMID: 33349646</identifier><language>eng</language><publisher>Singapore: Springer Singapore</publisher><subject>14 ; 14/19 ; 42/89 ; 631/80/642/1624 ; 631/80/83/2359 ; 631/80/86/2369 ; 82/1 ; 82/58 ; 96/109 ; 96/95 ; Aldolase ; AMP-Activated Protein Kinases - deficiency ; AMP-Activated Protein Kinases - genetics ; AMP-Activated Protein Kinases - metabolism ; Animals ; Biomedical and Life Sciences ; Cell Biology ; Fructose-Bisphosphate Aldolase - genetics ; Fructose-Bisphosphate Aldolase - metabolism ; Gene Expression Regulation - drug effects ; Glucose - metabolism ; Glucose - pharmacology ; HEK293 Cells ; Humans ; Letter to the Editor ; Life Sciences ; Lysosomes - metabolism ; Mechanistic Target of Rapamycin Complex 1 - metabolism ; Mice ; Mutagenesis, Site-Directed ; Regulatory-Associated Protein of mTOR - chemistry ; Regulatory-Associated Protein of mTOR - metabolism ; Signal Transduction - drug effects</subject><ispartof>Cell research, 2021-04, Vol.31 (4), p.478-481</ispartof><rights>The Author(s) 2020</rights><rights>The Author(s) 2020. 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Grahame</creatorcontrib><creatorcontrib>Lin, Sheng-Cai</creatorcontrib><title>Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1</title><title>Cell research</title><addtitle>Cell Res</addtitle><addtitle>Cell Res</addtitle><subject>14</subject><subject>14/19</subject><subject>42/89</subject><subject>631/80/642/1624</subject><subject>631/80/83/2359</subject><subject>631/80/86/2369</subject><subject>82/1</subject><subject>82/58</subject><subject>96/109</subject><subject>96/95</subject><subject>Aldolase</subject><subject>AMP-Activated Protein Kinases - deficiency</subject><subject>AMP-Activated Protein Kinases - genetics</subject><subject>AMP-Activated Protein Kinases - metabolism</subject><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Cell Biology</subject><subject>Fructose-Bisphosphate Aldolase - genetics</subject><subject>Fructose-Bisphosphate Aldolase - metabolism</subject><subject>Gene Expression Regulation - drug effects</subject><subject>Glucose - metabolism</subject><subject>Glucose - pharmacology</subject><subject>HEK293 Cells</subject><subject>Humans</subject><subject>Letter to the Editor</subject><subject>Life Sciences</subject><subject>Lysosomes - metabolism</subject><subject>Mechanistic Target of Rapamycin Complex 1 - metabolism</subject><subject>Mice</subject><subject>Mutagenesis, Site-Directed</subject><subject>Regulatory-Associated Protein of mTOR - chemistry</subject><subject>Regulatory-Associated Protein of mTOR - metabolism</subject><subject>Signal Transduction - drug effects</subject><issn>1001-0602</issn><issn>1748-7838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kU1PHSEUhomp8fsPuGhIuunCsQcGBmZjcnOjbaNVY3RNmBmYO5YLFmY0_fdFr9XWhQsCyXnOyzl5ENoncEiglF8SI4zSAigUAIxXhVxDW0QwWQhZyg_5DUAKqIBuou2UbgEoZ5xsoM2yLFldsWoLnc9cF5xOBg8Ja5yMTyFim08TxgV24QFr3-HF0C9w76Y2JHOA3eB_Dr7HY8CzH5enT8Ty-uJqTnbRutUumb3newfdnBxfz78VZxdfv89nZ0XLBBuLitmS1nVtqsYCN5JVRNvGGtaKPJeo6gZa0tGuq8GKumOUa2m0bCS1XEAL5Q46WuXeTc3SdK3xY9RO3cVhqeNvFfSg_q_4YaH6cK8kIZxJkgM-PwfE8GsyaVTLIbXGOe1NmJKiTFACnHOa0U9v0NswRZ_XU5SDkMBqLjNFV1QbQ0rR2JdhCKhHXWqlS2Vd6kmXemz6-O8aLy1__WSgXAEpl3xv4uvf78T-ATHcnoQ</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>Li, Mengqi</creator><creator>Zhang, Chen-Song</creator><creator>Feng, Jin-Wei</creator><creator>Wei, Xiaoyan</creator><creator>Zhang, Cixiong</creator><creator>Xie, Changchuan</creator><creator>Wu, Yaying</creator><creator>Hawley, Simon A.</creator><creator>Atrih, Abdelmadjid</creator><creator>Lamont, Douglas J.</creator><creator>Wang, Zhichao</creator><creator>Piao, Hai-Long</creator><creator>Hardie, D. 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| subjects | 14 14/19 42/89 631/80/642/1624 631/80/83/2359 631/80/86/2369 82/1 82/58 96/109 96/95 Aldolase AMP-Activated Protein Kinases - deficiency AMP-Activated Protein Kinases - genetics AMP-Activated Protein Kinases - metabolism Animals Biomedical and Life Sciences Cell Biology Fructose-Bisphosphate Aldolase - genetics Fructose-Bisphosphate Aldolase - metabolism Gene Expression Regulation - drug effects Glucose - metabolism Glucose - pharmacology HEK293 Cells Humans Letter to the Editor Life Sciences Lysosomes - metabolism Mechanistic Target of Rapamycin Complex 1 - metabolism Mice Mutagenesis, Site-Directed Regulatory-Associated Protein of mTOR - chemistry Regulatory-Associated Protein of mTOR - metabolism Signal Transduction - drug effects |
| title | Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1 |
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