Modulating skin colour: role of the thioredoxin and glutathione systems in regulating melanogenesis

Different skin colour among individuals is determined by the varying amount and types of melanin pigment. Melanin is produced in melanocytes, a type of dendritic cell located in the basal layer of the epidermis, through the process of melanogenesis. Melanogenesis consists of a series of biochemical...

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Veröffentlicht in:	Bioscience reports 2021-05, Vol.41 (5)
Hauptverfasser:	Lu, Yaoying, Tonissen, Kathryn F, Di Trapani, Giovanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine kinase Adenosine monophosphate Animals Antioxidants c-Kit protein Chemical Biology Color Cyclic AMP Dendritic cells Enzymes Epidermis Glutathione Glutathione - metabolism Humans Hyperpigmentation Kinases Melanin Melanins - biosynthesis Melanocytes Molecular Bases of Health & Disease Molecular Interactions Molecular weight Oxidation Oxidative stress Peptides Pheomelanin Phosphorylation Polymerization Protein kinase A Proteins Reactive oxygen species Reagents Reductases Review Signal transduction Signaling Skin Pigmentation Stem cell factor Stem cells Thioredoxin Thioredoxins - metabolism Transcription factors Tyrosinase Ultraviolet radiation Wnt protein β-Catenin
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