Systolic Blood Pressure on Admission Predicts In‐Hospital Mortality Among Patients Presenting With Acute Coronary Syndromes: The Greek Study of Acute Coronary Syndromes

The authors sought to evaluate whether the level of systolic blood pressure (SBP) on hospital admission is an independent prognostic factor for in‐hospital mortality of patients hospitalized with acute coronary syndrome (ACS). From October 2003 to September 2004, 2172 consecutive patients with ACS w...

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Veröffentlicht in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2008-05, Vol.10 (5), p.362-366
Hauptverfasser: Pitsavos, Christos, Panagiotakos, Demosthenes, Zombolos, Spyros, Mantas, Yannis, Antonoulas, Antonis, Stravopodis, Petros, Kogias, Yannis, Kourlaba, Georgia, Tsiamis, Eleftherios, Stefanadis, Christodoulos
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container_issue 5
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container_title The journal of clinical hypertension (Greenwich, Conn.)
container_volume 10
creator Pitsavos, Christos
Panagiotakos, Demosthenes
Zombolos, Spyros
Mantas, Yannis
Antonoulas, Antonis
Stravopodis, Petros
Kogias, Yannis
Kourlaba, Georgia
Tsiamis, Eleftherios
Stefanadis, Christodoulos
description The authors sought to evaluate whether the level of systolic blood pressure (SBP) on hospital admission is an independent prognostic factor for in‐hospital mortality of patients hospitalized with acute coronary syndrome (ACS). From October 2003 to September 2004, 2172 consecutive patients with ACS were included in the study (76% men). The in‐hospital mortality rate was 3.2% in male and 5.7% in female patients (overall, 82 deaths; P=.009). An inverse association was observed between in‐hospital mortality rate and levels of SBP (140 mm Hg, 2.6%; P
doi_str_mv 10.1111/j.1751-7176.2008.07619.x
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From October 2003 to September 2004, 2172 consecutive patients with ACS were included in the study (76% men). The in‐hospital mortality rate was 3.2% in male and 5.7% in female patients (overall, 82 deaths; P=.009). An inverse association was observed between in‐hospital mortality rate and levels of SBP (&lt;100 mm Hg, death rate 17.8%; 100–120 mm Hg, 3.7%; 120–140 mm Hg, 2.9%; &gt;140 mm Hg, 2.6%; P&lt;.001). Women, hypertensives, diabetics, dyslipidemics, and older patients had higher levels of SBP compared with other groups. The SBP of patients who received thrombolytic agents was lower than that of those who did not receive this therapy. Multi‐adjusted analysis revealed that a 10‐mm Hg increment in SBP was associated with a 27% lower likelihood of death during hospitalization (odds ratio, 0.73; 95% confidence interval, 0.66–0.90). 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From October 2003 to September 2004, 2172 consecutive patients with ACS were included in the study (76% men). The in‐hospital mortality rate was 3.2% in male and 5.7% in female patients (overall, 82 deaths; P=.009). An inverse association was observed between in‐hospital mortality rate and levels of SBP (&lt;100 mm Hg, death rate 17.8%; 100–120 mm Hg, 3.7%; 120–140 mm Hg, 2.9%; &gt;140 mm Hg, 2.6%; P&lt;.001). Women, hypertensives, diabetics, dyslipidemics, and older patients had higher levels of SBP compared with other groups. The SBP of patients who received thrombolytic agents was lower than that of those who did not receive this therapy. Multi‐adjusted analysis revealed that a 10‐mm Hg increment in SBP was associated with a 27% lower likelihood of death during hospitalization (odds ratio, 0.73; 95% confidence interval, 0.66–0.90). 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subjects Aged
Blood Pressure - physiology
Female
Follow-Up Studies
Greece - epidemiology
Hospital Mortality - trends
Humans
Male
Myocardial Infarction - mortality
Myocardial Infarction - physiopathology
Odds Ratio
Original Papers
Patient Admission
Prognosis
Retrospective Studies
Risk Factors
Syndrome
Systole
title Systolic Blood Pressure on Admission Predicts In‐Hospital Mortality Among Patients Presenting With Acute Coronary Syndromes: The Greek Study of Acute Coronary Syndromes
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