The Brain AT2R—a Potential Target for Therapy in Alzheimer’s Disease and Vascular Cognitive Impairment: a Comprehensive Review of Clinical and Experimental Therapeutics

Dementia is a potentially avertable tragedy, currently considered among the top 10 greatest global health challenges of the twenty-first century. Dementia not only robs individuals of their dignity and independence, it also has a ripple effect that starts with the inflicted individual’s family and p...

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Veröffentlicht in:	Molecular neurobiology 2020-08, Vol.57 (8), p.3458-3484
Hauptverfasser:	Ahmed, Heba A., Ishrat, Tauheed
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer's disease Amyloid Amyloid beta-Peptides - pharmacology Angiotensin Angiotensin II Angiotensin Receptor Antagonists - pharmacology Animals Biomedical and Life Sciences Biomedicine Brain - drug effects Cell Biology Clinical trials Cognitive ability Cognitive Dysfunction - drug therapy Dementia Dementia disorders Epidemiology Etiology Health care Humans Insulin Neurobiology Neurodegenerative diseases Neurology Neurosciences Pathophysiology Phosphorylation Renin Renin-Angiotensin System - drug effects Risk factors Tau protein Therapeutic applications Therapeutic targets Vascular dementia
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