The antioxidant MnTBAP does not effectively downregulate CD4 expression in T cells in vivo

The antioxidant MnTBAP was previously shown to down-regulate the surface expression of CD4 molecule in T cells. This observation obviously holds great potential impact in a number of pathological human conditions, including autoimmunity. Three different single doses of MnTBAP reduced the frequency o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of neuroimmunology 2021-05, Vol.354, p.577544-577544, Article 577544
Hauptverfasser:	Manouchehri, Navid, Guisso, Dikran R., Hussain, Rehana Z., Minassian, Berge A., Stüve, Olaf
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models therapy CD4 MnTBAP Experimental autoimmune encephalomyelitis Multiple sclerosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!