Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

As the coronavirus disease 2019 (COVID-19) pandemic rages on, it is important to explore new evolution-resistant vaccine antigens and new vaccine platforms that can produce readily scalable, inexpensive vaccines with easier storage and transport. We report here a synthetic biology-based vaccine plat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-05, Vol.118 (18), p.1-10
Hauptverfasser:	Maeda, Denicar Lina Nascimento Fabris, Tian, Debin, Yu, Hanna, Dar, Nakul, Rajasekaran, Vignesh, Meng, Sarah, Mahsoub, Hassan M., Sooryanarain, Harini, Wang, Bo, Heffron, C. Lynn, Hassebroek, Anna, LeRoith, Tanya, Meng, Xiang-Jin, Zeichner, Steven L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence Amino acids Animal models Animals Antibodies, Viral - blood Antigens Bacteria Biological Sciences Cell surface Conserved sequence Coronaviridae Coronaviruses COVID-19 COVID-19 - prevention & control COVID-19 Vaccines - immunology Diarrhea Disease Models, Animal E coli Escherichia coli - genetics Genome, Bacterial Genomes Immune system Interferon Interferon-gamma - blood Jejunum Pandemics Peptides Porcine epidemic diarrhea virus - immunology Public health Residues RNA, Viral - analysis SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Swine Transmissible gastroenteritis Vaccines Vaccines, Inactivated - immunology Vaccines, Synthetic - immunology Viral diseases Viral Fusion Proteins - immunology Viral Vaccines - immunology Viruses γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!