Sustained Inhibition of NF-κB Activity Mitigates Retinal Vasculopathy in Diabetes

This study investigated the effects of long-term NF-κB inhibition in mitigating retinal vasculopathy in a type 1 diabetic mouse model (Akita, Ins2Akita). Akita and wild-type (C57BL/6J) male mice, 24 to 26 weeks old, were treated with or without a selective inhibitor of NF-κB, 4-methyl-N1-(3-phenyl-p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American journal of pathology 2021-05, Vol.191 (5), p.947-964
Hauptverfasser: Homme, Rubens P., Sandhu, Harpal S., George, Akash K., Tyagi, Suresh C., Singh, Mahavir
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!