Integrated Molecular Docking with Network Pharmacology to Reveal the Molecular Mechanism of Simiao Powder in the Treatment of Acute Gouty Arthritis

Background. The incidence of gout has been rapidly increasing in recent years with the changing of diet. At present, modern medications used in the clinical treatment of gout showed several side effects, such as gastrointestinal damage and the increased risk of cardiovascular disease. The traditiona...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2021, Vol.2021, p.5570968-15
Hauptverfasser:	Fan, Yihua, Liu, Wei, Jin, Yue, Hou, Xu, Zhang, Xuewu, Pan, Hudan, Lu, Hang, Guo, Xiaojing
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Arthritis Cardiovascular diseases Chinese medicine Computer programs Core protein Cyclin-dependent kinase 2 Disease DNA-directed RNA polymerase ESR1 protein Gout GRP78 protein Hypoxia-inducible factor 1 Inflammation Interleukin 17 Kaempferol Kidneys Lipopolysaccharides Nonsteroidal anti-inflammatory drugs Oxidative stress p53 Protein Pain Pharmacology Protein kinase Protein kinase C Proteins Quercetin Rheumatism Signal transduction Software Traditional Chinese medicine Tumor necrosis factor Tumor necrosis factor-TNF Uric acid
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