Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry

Proteomics has exposed a plethora of posttranslational modifications, but demonstrating functional relevance requires new approaches. Top-down proteomics of intact proteins has the potential to fully characterize protein modifications in terms of amount, site(s), and the order in which they are depo...

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Veröffentlicht in:	Molecular & cellular proteomics 2021-01, Vol.20, p.100070-100070, Article 100070
Hauptverfasser:	Brunner, Andrea M., Lössl, Philip, Geurink, Paul P., Ovaa, Huib, Albanese, P., Altelaar, A.F. Maarten, Heck, Albert J.R., Scheltema, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bora ETD Isomerism Mass Spectrometry phosphorylation positional isomers Protein Processing, Post-Translational Proteomics - methods Technological Innovation and Resources Top-down mass spectrometry
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