The Landscape of Recombination Events That Create Nonribosomal Peptide Diversity

Abstract Nonribosomal peptides (NRP) are crucial molecular mediators in microbial ecology and provide indispensable drugs. Nevertheless, the evolution of the flexible biosynthetic machineries that correlates with the stunning structural diversity of NRPs is poorly understood. Here, we show that reco...

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Veröffentlicht in:	Molecular biology and evolution 2021-05, Vol.38 (5), p.2116-2130
Hauptverfasser:	Baunach, Martin, Chowdhury, Somak, Stallforth, Pierre, Dittmann, Elke
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Discoveries Ecology Evolution, Molecular Evolutionary biology Ligases Models, Genetic Multigene Family Peptide Biosynthesis, Nucleic Acid-Independent - genetics Peptide Synthases - genetics Peptides Recombination, Genetic
Online-Zugang:	Volltext
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