Structural determinants of regulated proteolysis in pathogenic bacteria by ClpP and the proteasome

•As in eukaryotes, chambered proteases are essential for normal physiology in bacteria.•The timing and selection of specific substrates for degradation is incompletely understood.•Structural studies have revealed interactions between proteases and activators, providing new insight into how degradati...

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Veröffentlicht in:	Current opinion in structural biology 2021-04, Vol.67, p.120-126
Hauptverfasser:	Kahne, Shoshanna C, Darwin, K Heran
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Endopeptidase Clp - metabolism Proteasome Endopeptidase Complex Proteolysis Substrate Specificity
Online-Zugang:	Volltext
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