Association Between Immune Response to Cytomegalovirus and Cognition in the Health and Retirement Study

Abstract Chronic infections and the subsequent immune response have recently been shown to be risk factors for cognitive decline and Alzheimer disease and related dementias (ADRD). While some studies have shown an association between cytomegalovirus (CMV), a chronic and highly prevalent infection, a...

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Veröffentlicht in:	American journal of epidemiology 2021-05, Vol.190 (5), p.786-797
Hauptverfasser:	Stebbins, Rebecca C, Noppert, Grace A, Yang, Yang Claire, Dowd, Jennifer B, Simanek, Amanda, Aiello, Allison E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer's disease Antibody response Chronic Disease Chronic infection Cognition Cognition & reasoning Cognitive ability Cognitive Dysfunction - virology Confidence intervals Cross-Sectional Studies Cytomegalovirus Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Education Educational attainment Educational Status Female Humans IgG antibody Immune response Immune system Immunoglobulin G Immunoglobulin G - immunology Male Neurodegenerative diseases Original Contribution Prevalence Regression analysis Regression models Retirement Risk Factors Statistical analysis United States - epidemiology
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