Minor Contribution of Bone Marrow-Derived Endothelial Progenitors to the Vascularization of Murine Gliomas

Until recently, it was generally accepted that the vascularization of solid tumors occurred exclusively through the sprouting and co‐option from preexisting blood vessels. Growing evidence now suggests that bone marrow‐derived endothelial progenitor cells (EP) circulate in the blood and may play an...

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Veröffentlicht in:	Brain pathology (Zurich, Switzerland) Switzerland), 2003-10, Vol.13 (4), p.582-597
Hauptverfasser:	Machein, Márcia Regina, Renninger, Sabine, De Lima-Hahn, Elisete, Plate, Karl H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD Antigens, Differentiation - metabolism Blotting, Northern Bone Marrow - physiology CD11b Antigen - metabolism Cell Line, Tumor Endoglin Glial Fibrillary Acidic Protein - metabolism Glioma - metabolism Glioma - physiopathology Glioma - veterinary Glycoside Hydrolases - metabolism Hematopoietic Stem Cell Transplantation - methods Hematopoietic Stem Cells - physiology Immunohistochemistry Infection Lac Operon Leukocyte Common Antigens - metabolism Lung - metabolism Mice Mice, Inbred C57BL Mice, Transgenic Microglia - metabolism Microscopy, Confocal Neovascularization, Pathologic - physiopathology Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Receptors, Cell Surface Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - biosynthesis Spleen - metabolism Time Factors Vascular Cell Adhesion Molecule-1 - metabolism Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism von Willebrand Factor - metabolism
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